The Effect of High-Salted Mineral Water on Blood Pressure and Sodium Excretion

  • Park Seung Kyu (Department of Parasitology and Institute of Basic Medical Science, Wonju College of Medicine, Yonsei University) ;
  • Lee Hae Jin (Department of Biochemistry, Wonju College of Medicine, Yonsei University) ;
  • Kim Dong Heui (Department of Basic Science, Wonju College of Medicine, Yonsei University) ;
  • Deung Young Kun (Department of Basic Science, Wonju College of Medicine, Yonsei University) ;
  • Yang Eun Ju (Department of Biomedical Laboratory Science and Institute of Health Science, College of Health Science, Yonsei University) ;
  • Lim Soo Jung (Department of Biomedical Laboratory Science and Institute of Health Science, College of Health Science, Yonsei University) ;
  • Ryang Yong Suk (Department of Biomedical Laboratory Science and Institute of Health Science, College of Health Science, Yonsei University) ;
  • Kim Hyun Won (Department of Biochemistry, Wonju College of Medicine, Yonsei University) ;
  • Lee Kyu Jae (Department of Parasitology and Institute of Basic Medical Science, Wonju College of Medicine, Yonsei University)
  • Published : 2005.09.01

Abstract

High-salted mineral water (Daehan Deep Water, Korea) that is pumped up from below the sedimentary rock layer of Dadaepo, Busan, Korea has a composition similar with that of deep sea water. Under the well-being boom, the mineral water is processed for various uses including washing or oral administration. However, high concentrations of various minerals in the mineral water are suspected to affect on the physiology of human body, especially on blood pressure (BP). Here, we examined the effect of Hot Mineral(R), dried powder of the mineral water, on the change of BP. Sprague­Dawley rats were grouped and orally administered $2.5\%$ Hot Mineral(R) (group M), $2.5\%$ NaCl (group S) or normal water (group C). Excreted urine was collected in metabolic cage for 24 hours. The systolic blood pressure (SBP) of the group S was remarkably increased (P<0.005) compared with that of the group M and the group C, which showed little changes of the SBP during 2 weeks. While average daily sodium intake were 0.32 mg in the group C, 6.64 mg in the group M and 4.07 mg in the group S, average daily sodium excretion were 11.37 mg, 53.70 mg and 7.75 mg, respectively. These results indicate that the sodium excretion in the group M was much higher than the other two groups. In this study, we suppose that the plenty amount of minerals such as calcium, potassium and magnesium in Hot Mineral? have an effect not to increase the SBP and to prompt sodium excretion out of the body. Therefore, these results suggest that oral administration of appropriate amount of Hot Mineral(R) for limited period does not induce increased SBP.

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