KSBB Journal

The Korean Society for Biotechnology and Bioengineering (한국생물공학회)
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Selective Removal of Acetic Acid for the Effective Production of Succinic Acid using the Various Amino Extractants and Solvents

효율적 숙신산 생산을 위한 다양한 아민추출제와 용매를 이용한 아세트산의 선택적 추출제거

  • Huh Yun Suk (Department of Chemical and Biomolecular Engineering, Korea Advanced Institute of Science and Technology) ;
  • Hong Yeon Ki (Department of Chemical and Biological Engineering, Chungju National University) ;
  • Jun Young-Si (Department of Chemical and Biomolecular Engineering, Korea Advanced Institute of Science and Technology) ;
  • Hong Won Hi (Department of Chemical and Biomolecular Engineering, Korea Advanced Institute of Science and Technology)
  • 허윤석 (한국과학기술원 생명화학공학과) ;
  • 홍연기 (충주대학교 화공생물공학과) ;
  • 전영시 (한국과학기술원 생명화학공학과) ;
  • 홍원희 (한국과학기술원 생명화학공학과)
  • Published : 2005.06.01
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Abstract

Succinic acid has recently been drawing much interest as a raw material for biodegradable polymer. In this study acetic acid was removed by reactive extraction with various amines dissolved in various diluents. Distribution coefficients were determined as the kind of amines, diluents, and pHs of continuous phase. The extraction capacity increased with the polarity of diluent and the decrease of pH from the artificial binary solution. Based on the different extractability for succinic acid and acetic acid from the artificial binary solution, the removal of acetic acid from fermentation broth was investigated using various amines and diluents. In addition, the extractability and selectivity of CLA for succinic acid and acetic acid from fermentation broth were higher than that of straight solvent extraction.

최근 들어 카르복실산 중에서 숙신산은 생분해성 고분자의 원료물질로서 주목받고 있다. 본 연구에서는 다양한 아민추출제 및 희석제를 이용한 반응추출을 통해 숙신산 및 아세트산의 선택추출에 대한 연구를 하였다. 그 결과 활성희석제의 경우 2, 3차 아민의 추출능이 우수하였고, 비활성 희석제의 경우에는 4차 아민의 추출능이 보다 높게 나타났다. 전체적인 분배계수 값을 비교할 때 활성희석제를 이용한 반응추출이 효과적임을 알 수 있었다. 또한 실제 발효액을 이용한 반응추출 실험결과, 모사 수용액에 비하여 추출능이 현저히 감소함을 볼 수 있었는데 이는 발효액에 들어있는 여러 가지 불순물들이 반응추출을 저해하기 때문이다. 여러 불순물들에 대한 반응추출의 저해 영향은 아세트산에 비해 숙신산이 컸으며, 이를 통해 실제 발효액에서 숙신산을 정제하기 위해서는 불순물로 존재하는 아세트산을 선택적으로 추출하여 제거하는 분리공정을 적용하는 것이 효과적임을 알 수 있었다. 추출제의 물질전달 및 보다 빠른 반응성의 향상을 위해 CLA에 대한 분배계수 및 선택도 실험을 수행한 결과, pH 변화에 따라 분배계수 및 선택도가 증가함을 알 수 있었다.

Keywords

References

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