The Sedative Effects of Submucosal Midazolam in Children

소아 진정 시 구강 협점막하로 투여한 Midazolam의 효과에 관한 연구

  • Lee, Young-Eun (Department of Pediatric Dentistry, Ewha Womans University Graduate School of Clinical Dentistry) ;
  • Park, Mi-Eung (Department of Pediatric Dentistry, Ewha Womans University Graduate School of Clinical Dentistry) ;
  • Kim, Yun-Hee (Department of Pediatric Dentistry, Ewha Womans University Graduate School of Clinical Dentistry) ;
  • Jung, Sang-Hyuk (Departnent of Preventive Medicine, College of Medicine, Ewha Womans University) ;
  • Baek, Kwang-Woo (Department of Pediatric Dentistry, Ewha Womans University Graduate School of Clinical Dentistry)
  • 이영은 (이화여자대학교 임상치의학대학원 소아치과학교실) ;
  • 박미경 (이화여자대학교 임상치의학대학원 소아치과학교실) ;
  • 김윤희 (이화여자대학교 임상치의학대학원 소아치과학교실) ;
  • 정상혁 (이화여자대학교 의과대학 예방의학교실) ;
  • 백광우 (이화여자대학교 임상치의학대학원 소아치과학교실)
  • Published : 2005.12.31

Abstract

Purpose: This retrospective study assessed the effectiveness of submucosal (SM) midazolam (M), oral chloral hydrate (CH), hydroxyzine (H), and nitrous oxide (N) 99 uncooperative pediatric dental patients over 182 sedation sessions. Methods: Selection criteria included good medical health (ASA I), from 2 to 6 years of age, uncooperative behavior, and the need for restorations and dental surgery. The children who was administerated with CH H, N was Group 1 (48 case). The children who was administerated with CH, H, N, M was Group 2 (51 case). All the patients received oral CH (50-70 mg/Kg), H (1 mg/Kg) and N (less than 50%). Additionally the Group 2 received SM midazolam (0.1-0.2 mg/kg). Behavior response was rated as quiet (Q), crying (C), movement (M), or struggling (S) every 5 minutes through operative procedures. Behavior response rating was assigned to Houpt scale of Overall behavior. Data was analyzed using Chi-Square Test. Results: The Group 2 had more effective (88.2%) than the Group 1 (68.8%)(P = 0.05). Also, vomiting response decreased in the Group 2 (94.4%) than those with oral administration of chloral hydrate alone without SM midazolam (77.1%)(P = 0.05). Conclusions: SM midazolam improved the quality of sedation and vomiting response.

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