Natural Product Sciences

The Korean Society of Pharmacognosy (한국생약학회)
권호 표지

Antioxidant Constituents from Portulaca oleracea

  • Choi, Bong-Rak (College of Pharmacy, Chungbuk National University,Bioland Ltd.) ;
  • Hong, Seong-Su (College of Pharmacy, Chungbuk National University) ;
  • Han, Xiang Hua (College of Pharmacy, Chungbuk National University) ;
  • Hwang, Ji-Sang (College of Pharmacy, Chungbuk National University) ;
  • Lee, Min-Hee (College of Pharmacy, Chungbuk National University,Crown Pharmaceutical Co. Ltd.) ;
  • Hur, Jae-Doo (Crown Pharmaceutical Co. Ltd.) ;
  • Hwang, Bang-Yeon (College of Pharmacy, Chungbuk National University) ;
  • Ro, Jai-Seup (College of Pharmacy, Chungbuk National University)
  • Published : 2005.12.01
Download PDF
⟨ Previous Next ⟩

Abstract

The repeated column chromatographic separation of the EtOH extract of Portulaca oleracea afforded seven compounds. The structures of these isolates were identified as bergapten (1), umbelliferone (2), daidzein (3), genistein (4), protocatechuic acid (5), ferulic acid (6), and gallic acid (7) by the analysis of physico-chemical and spectral data. Their antioxidant effect on free radical scavenging was evaluated in the DPPH assay.

Keywords

References

  1. An, R.B., Park, B.Y., Kim, J.H., Kwon, O.K., Lee, J., Min, B.S., Ahn, K.S., Oh, S.R., and Lee, H.K., Coumarins and chromones from Angelica genujlexa. Nat. Prod Sci. 11, 79-84 (2005)
  2. Blade, A.M., Claeys, M., Pieters, L.A., Wray, V., and Vlietinck, A.J., Ferulic acid esters from stem bark of Pavetta owariensis. Phytochemistry 30, 1024-1026 (1991) https://doi.org/10.1016/0031-9422(91)85302-G
  3. Blois, M.S., Antioxidant determination by the use of a stable free radical. Nature 181, 1199-1200 (1958) https://doi.org/10.1038/1811199a0
  4. Cha, B.C., Lee, S.B., Rhim, T.J., and Lee, K.H., Constituents of antioxidative activity and free radical scavenging effect from Galla Rhois (Rhus javanica Linne). Kor. J. Pharmacogn. 31, 185-189 (2000)
  5. Fujika, T., Furumi, K., Fujh, H., Okabe, H., Mihashi, K., Nakano, Y., Matsunaga, H., Katano, M., and Mori, M., Antiproliferative constituents from umbelliferae plants. Chem. Pharm. Bull. 47, 96-100 (1999) https://doi.org/10.1248/cpb.47.96
  6. Habtemariam, S., Harvey, A.L., and Waterman, P.G., The muscle relaxant properties of Portulaca oleracea are associated with high concentrations of potassium ions. J. Ethnopharmacol. 40, 195-200 (1993) https://doi.org/10.1016/0378-8741(93)90068-G
  7. Hwang, B.Y., Kim, H.S., Lee, J.H., Hong, Y.S., Ro, J.S., Lee, K.S., and Lee, J.J., Antioxidant benzoylated favan-3-ol glycoside from Celastrus orbiculatus. J. Nat. Prod. 64, 82-84 (2001) https://doi.org/10.1021/np000251l
  8. Jung, B.S., and Shin M.K., Encyclopedia of Illustrated Korean Natural Drugs, Young Lim Sa, Seoul, 1989, pp. 350-35l
  9. Karimi, G., Hosseinzadeh, H., and Ettehad, N., Evaluation of the gastric antiulcerogenic effects of Portulaca oleracea L. extracts in mice. Phytother. Res. 18, 484-487 (2004) https://doi.org/10.1002/ptr.1463
  10. Krishnamurty, H.G., and Prasad, J.S., Isotlavones of Moghania macrophylla. Phytochemistry 19, 2797-2798 (1980) https://doi.org/10.1016/S0031-9422(00)83979-5
  11. Lee, H.J., Lee, B.J., Lee, D.S., and Seo, Y.W., DPPH radical scavenging effect and in vitro lipid peroxidation inhibition by Portulaca oleracea. Korean J. Biotechnol. Bioeng. 18, 165-169 (2003)
  12. Lim, J.P., and Suh, E.S., Hepatoprotective, diuretic and antiinflammatory activities of the extract from Portulaca oleracea L. Korean J. Medicinal Crop Sci. 8, 189-193 (2000)
  13. Lim, M.K. and Kim, M.R., Antimicrobial activity of methanol extract from Soibirhym (Portulaca oleracea) against food spoilage disease microorganisms and the composition of the extract. Korean J. Soc. Food Cookery Sci. 17, 565-570 (2001)
  14. Liu, L., Howe, P., Zhou, Y.F., Xu, Z.Q., Hocart, C., and Zhan, R., Fatty acids and $\beta$-carotene in australian purslane (Portulaca oleracea) varieties. J. Chromatogr. A. 893, 207-213 (2000) https://doi.org/10.1016/S0021-9673(00)00747-0
  15. Malek, F., Boskabady, M.H., Borushaki, M.T., and Tohidi, M., Bronchodilatory effect of Portulaca oleracea in airways of asthmatic patients. J. Ethnopharmacol. 93, 57-62 (2004) https://doi.org/10.1016/j.jep.2004.03.015
  16. Mizutani, M., Hashidoko, Y., and Tahara, S., Factors responsible for inhibiting the motility of zoospores of the phytopathogenic fungus Aphanomyces cochlioides isolated from the non-host plant Portulaca oleracea. FEBS Lett. 438, 236-240 (1998) https://doi.org/10.1016/S0014-5793(98)01308-8
  17. Oh, K.B., Chang, I.M., Hwang, K.J., and Mar, W., Detection of antifungal activity in Portulaca oleracea by a single-cell bioassay system. Phytother. Res. 14, 329-332 (2000) https://doi.org/10.1002/1099-1573(200008)14:5<329::AID-PTR581>3.0.CO;2-5
  18. Okwuasaba, F., Ejike, C., and Parry, O., Effects of extracts of Portulaca oleracea on skeletal muscle in vitro. J. Ethnopharmacol. 21, 55-63 (1987) https://doi.org/10.1016/0378-8741(87)90094-8
  19. Park, J.S., and Kim, K.U., Identification of physiologically active compounds from Purslane (Portulaca oleracea L.). Kor. J. Weed Sci. 8, 169-175 (1988)
  20. Parry, O., Okwuasaba, F., and Ejike, C., Effect of an aqueous extract of Portulaca oleracea leaves on smooth muscle and rat blood pressure. J. Ethnopharmacol. 22, 33-44 (1988) https://doi.org/10.1016/0378-8741(88)90228-0
  21. Rashed, A.N., Afifi, F.U., and Disi, A.M., Simple evaluation of the wound healing activity of a crude extract of Portulaca oleracea L. (growing in Jordan) in Mus musculus JVI-1. J. Ethnopharmacol. 88, 131-136 (2003) https://doi.org/10.1016/S0378-8741(03)00194-6
  22. Sakai, N., Inada, K., Okamoto, M., Shizuri, Y., and Fukuyama, Y., Portuloside A,A monoterpene glucoside, from Portulaca oleracea. Phytochemistry 42, 1625-1628 (1996) https://doi.org/10.1016/0031-9422(96)00202-6
  23. Shin, K.H., Kang, S.S., and Chi, H.J., Analysis of the coumarin constituents in Peucedanii Radix. Kor. J. Pharmacogn. 23, 20-23 (1992)
  24. Verma, O.P., Kumar, S., and Chatterjee, S.N., Antifertility effects of common edible Portulaca oleracea on the reproductive organs of male albino mice. Indian J. Med. Res. 75, 301-310 (1982)