동의신경정신과학회지 (Journal of Oriental Neuropsychiatry)
- 제16권1호
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- Pages.43-66
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- 2005
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- 1226-6396(pISSN)
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- 2234-4942(eISSN)
초기 알츠하이머형 치매환자에 대한 건뇌탕(健腦湯)의 효능 -12 개월 임상 연구-
The Effects on Kunneotang of Patients with Early Dementia of Alzheimer Type -12 Months Clinical Study-
- 엄효진 (경희대학교 한의과대학 한방신경정신과학교실) ;
-
김종우
(경희대학교 한의과대학 한방신경정신과학교실)
;
-
박은혜
(고려대학교 심리학과)
;
- 김현택 (고려대학교 심리학과) ;
-
황의완
(경희대학교 한의과대학 한방신경정신과학교실)
- Eom, Hoy-Jin (Dept. of Neuropsychiatry, college of Oriental Medicine, Kyung Hee University) ;
-
Kim, Jong-Woo
(Dept. of Neuropsychiatry, college of Oriental Medicine, Kyung Hee University)
;
-
Park, Eun-Hye
(Department of psychology, Korea University)
;
- Kim, Hyun-Taek (Department of psychology, Korea University) ;
-
Whang, Wei-Wan
(Dept. of Neuropsychiatry, college of Oriental Medicine, Kyung Hee University)
- 발행 : 2005.06.30
초록
Object : This study was designed to asses the protective effects of Kunneo tang on cognitive decline of the patients with early DAT. Method : Before administered with Kunneotang, 16 patients with early DAT were measured by auditory ERP, MMSE-K and K-DRS. During 12 months the patients with early DAT were administered with Kunneotang. After 12months the patients were measured by the same examinations again. Result : 1. The total score of MMSE-K decreased but it was not significant. 2. The total score of K-DRS increased but it was not significant. Among the five criteria(attention, memory, initiation/perseveration, construction, conceptualization), Initiation/perseveration score signifcantly decreased and there were no significant differences in the other scores. But, memory mean score had a tendency to increase. 3. The latency of ERP P300 component increased but it was not significant and the amplitude of ERP P300 component showed the significant difference. Conclusion : The results suggest that Kunneotang may have protective effects on cognitive decline in the patients with early DAT.