대한한방내과학회지 (The Journal of Internal Korean Medicine)
- 제26권2호
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- Pages.398-408
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- 2005
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- 1226-9174(pISSN)
십육미류기음(十六味流氣飮)이 FRTL-5 갑상선 세포의 DNA와 cAMP의 합성 및 MHC-class II의 발현에 미치는 영향
Effects of Sipyukmiyukieum on DNA Synthesis, cAMP Synthesis and MHC-class II Expression of FRTL-5 Thyroid Cells
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Kim, Byoung-Woo
(Department of Internal Medicine, Oriental Hospital of Sangji University) ;
- Yi, Jae-Eun (Department of Internal Medicine, Oriental Hospital of Sangji University)
- 발행 : 2005.06.30
초록
Objective: Graves' disease encompasses hyperthyroidism and diffused goiter associated with auto-antibodies to the thyroid stimulating hormone(TSH) receptors. In clinical environment, treatments of Graves' disease have many side effects such as recurrence and hypothyroidism. We've studied the effects of Sipyukmiyukieum on DNA synthesis, cAMP synthesis, and MHC-class II expression of FRTL-5 thyroid cells were studied. Methods: DNA synthesis was investigated by using BrdU staining and cAMP synthesis by ELISA kit, and expression of
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