The Korea Journal of Herbology (대한본초학회지)
- Volume 20 Issue 3
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- Pages.19-27
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- 2005
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- 1229-1765(pISSN)
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- 2288-7199(eISSN)
Cytotoxicity and Antioxidant Activities of the Yeonkyo-san and Its ingredients
연교산과 구성약재에 대한 항암 및 항산화효과
- Lee, Jin-Tae (Dept. of Cosmeceutical Science, Daegu Haany University) ;
- Lee, Chang-Eon (Dept. of Cosmeceutical Science, Daegu Haany University) ;
- Son, Jun-Ho (Dept. of Cosmeceutical Science, Daegu Haany University) ;
- Lee, Jin-Young (Dept. of Cosmeceutical Science, Daegu Haany University) ;
- Park, Tae-Soon (Dept. of Cosmeceutical Science, Daegu Haany University) ;
- Lee, In-Cheol (Dept. of Cosmeceutical Science, Daegu Haany University) ;
- Cheon, Soon-Ju (Dept. of Cosmeceutical Science, Daegu Haany University) ;
- Pyeon, Jeong-Ran (Dept. of Cosmeceutical Science, Daegu Haany University) ;
- Jee, Seon-Young (Dept. of Oriental Medicine, Daegu Haany University) ;
- Jo, Cheol-Hun (Advanced Radiation Technology Institute) ;
- An, Bong-Jeun (Dept. of Cosmeceutical Science, Daegu Haany University)
- 이진태 (대구한의대학교 화장품약리학과) ;
- 이창언 (대구한의대학교 화장품약리학과) ;
- 손준호 (대구한의대학교 화장품약리학과) ;
- 이진영 (대구한의대학교 화장품약리학과) ;
- 박태순 (대구한의대학교 화장품약리학과) ;
- 이인철 (대구한의대학교 화장품약리학과) ;
- 천순주 (대구한의대학교 화장품약리학과) ;
- 편정란 (대구한의대학교 화장품약리학과) ;
- 지선영 (대구한의대학교 한의학과) ;
- 조철훈 (한국원자력연구소 방사선연구원) ;
- 안봉전 (대구한의대학교 화장품약리학과)
- Published : 2005.09.30
Abstract
Objectives : The antioxidant activities of Yeonkyo-san and its ingredient were investigated for industrial application. Methods : We experimented radical scavenging effect, superoxide dismutase and cytotoxicity effect of various cancer cell. Results : The result were obtained as follows : Primary testing of cytotoxicity of Yeonkyo-san and ingredient was done for G361. B16F10, MDA and A549 cell lines. Yeonkyo-san and ingredient water extract, ethanol extract showed cytotoxicity of over 90% respectively against cell line. The electron donating ability(EDA) of water extract from the Yeonkyo-san was higher than 60%, ethanol extract from the Yeonkyo-san was over 80% at 1000 ppm. The electron donating ability(EDA) of water extract and ethanol extract from the Yeonkyo-san ingredients were increased as well. SOD-like activity was high as 75% in 700 ppm, it was increased. All the other samples showed less than 40% SOD-like activity. Conclusions : The results indicated that water extract and ethanol extract of Yeonkyo-san and ingredient can be used as a natural ingredient with biological functions in cosmetic and food composition.