Journal of Physiology & Pathology in Korean Medicine (동의생리병리학회지)

The Physiological Society of Korean Medicine and The Society of Pathology in Korean Medicine (대한동의생리학회·한의병리학회)
권호 표지

Cytotoxic Activity of $13(E)-labd-13-ene-8{\alpha}$, 15-diol on Human Epithelioid Carcinoma Cells

  • Lim, Jin-A (Department of Herbal Resources, Professional Graduate School of Oriental Medicine and Institute of Basic Natural Sciences, Wonkwang University) ;
  • Kwag, Jung-Sook (Department of Dental Hygiene, Mokpo Science College) ;
  • Perry, Nigel B. (Plant Extracts Research Unit, New Zealand Institute for Crop & Food Research Ltd, Department of Chemistry, Otago University) ;
  • Kim, Il-Kwang (Division of Bionano Chemistry, Wonkwang University) ;
  • Baek, Seung-Hwa (Department of Herbal Resources, Professional Graduate School of Oriental Medicine and Institute of Basic Natural Sciences, Wonkwang University)
  • Published : 2005.02.25
Download PDF
⟨ Previous Next ⟩

Abstract

The cytotoxic activity of $13(E)-labd-13-ene-8{\alpha}$, 15-diol (1), isolated from the ethanol extract of Brachyglottis monroi, was evaluated against human oral epithelioid carcinoma cells(KB).

Keywords

References

  1. Connor, H. E., Edger, E.: Name changes in the indigenous New Zealand flora, 1960-1986 and Nomina Nova IV, 1983-1986. N. Z. J. Bot. 25, 2255-2258, 1987.
  2. Allan, H. H.: Flora of New Zealand. Indigenous Tracheopphyta, Psilopsida, Lycopsida, Filicopsida, Gymnospermae, Dicotyledones; DSIR: Wellington; Vol. 1, 1960.
  3. Riley, M.: Maori Healing and Herbal. Paraparaumu. New Zealand: Viking Sevenseas N. Z. Ltd. 1994.
  4. Kulanthaivel, P., Benn, M. H.: A new truxillate and some flavonoid esters from the leaf gum of Traversia baccharoides Hook. f. Can. J. Chem. 64, 514-519, 1986.
  5. Hadden, C. E., Martin, G. E., Krishnamurthy, V. V.: Magn. Reson, Chem. 38, 143-147, 2000.
  6. Braun, S., Kalinowski, H. O., Berger, S. 100 and more basic NMR experiments.: VCH Wiley: Weinheim. New York, 1996.
  7. Calabuig, M. T., Cortes, M., Francisco, C. G., Hernandez, R., Suarez, E.: Labdane diterpenes from Cistus synphytifolius. Phytochem. 20, 2255-2258, 1981.
  8. Carmichael, J., Degraff, W. G., Gazdar, A. F., Minna, J. D., Mitchell, J. B.: Evalution of a tetrazolium-based semiautomated colorimetric assay: Assessment of chemosensitivity testing. Cancer Res. 47, 936-942, 1987.
  9. Mossmann, T. J.: Rapid colorimetric assays for cellular growth and survival: application to proliferation and cytotoxicity assays. Immunol. Methods 65, 55-63, 1983.
  10. Zahra, J. P., Kauvet, F., Coste-Maniere, I., Martres, P., Perfetti, P., Waegall, B.: Oxidative degradation of the sclareol side chain: Hemisynthese of ambergris derivatives using in the key steps palladium complexes or ruthenium tetroxide generated situ. Bull. Soc. Chim. Fr. 134, 1001, 1997.
  11. Carman, R. M.: Optical rotation and structure in the labdane series of diterpenoids. Aust. J. Chem.19, 629-642, 1966.
  12. Pozo-Cuisado, E., Alvarez-Barrientos, A., Mulero-Navarro, S., Santiago-Josefat, B., Fernandez- Salguero, P. M.: The antiproliferative activity of resveratrol results in apoptosis in MCF-7 but not in MDA-MB-231 human breast cancer cells: cell-specific alteration of the cell cycle. Biochem. Pharmacol. 64, 1375-1386, 2002.
  13. Inoue, M., Suzuki, R., Sakaguchi, N., Li, Z., Takeda, T., Ogihara, Y., Jiang, B. Y., Chen, Y.: Selective induction of cell death in cancer cells by gallic acid. Biol, Pharm. Bull. 18, 1526-1530, 1995.
  14. Lee, Y. J., Liao, P. H., Chen, W. K., Yang, C. C.: Perferential cytotoxicity of caffeic acid phenethyl ester analogues on oral cancer cells. Cancer Lett. 153, 51-56, 2000.