Korean Journal of Acupuncture

Society for Meridian and Acupoint (경락경혈학회)
권호 표지

Effect of Ephedrae Herbal Acupuncture Solution(EHS) on the Release of Thymus and Activation-Regulated Chemokine (TARC) in Human Bronchial Epithelial Cell

마황(麻黃) 약침액(藥鍼液)이 사람 기관지 상피세포의 TARC 분비에 미치는 효과

  • Chou, Yu-Shih (Dept. of Acupuncture & Moxibustion, College Oriental Medicine Daegu Haany University) ;
  • Seo, Jung-Chul (Dept. of Acupuncture & Moxibustion, College Oriental Medicine Daegu Haany University) ;
  • Lim, Seong-chul (Dept. of Acupuncture & Moxibustion, College Oriental Medicine Daegu Haany University) ;
  • Jung, Tae-Young (Dept. of Acupuncture & Moxibustion, College Oriental Medicine Daegu Haany University) ;
  • Han, Sang-Won (Dept. of Acupuncture & Moxibustion, College Oriental Medicine Daegu Haany University)
  • 주유적 (대구한의대학교 한의과대학 침구학교실) ;
  • 서정철 (대구한의대학교 한의과대학 침구학교실) ;
  • 임성철 (대구한의대학교 한의과대학 침구학교실) ;
  • 정태영 (대구한의대학교 한의과대학 침구학교실) ;
  • 한상원 (대구한의대학교 한의과대학 침구학교실)
  • Published : 2005.03.27
Download PDF
⟨ Previous Next ⟩

Abstract

Chemokines are important for the recruitment of leukocytes, which is essential in host defense to the sites of infection. The thymus and activation-regulated chemokine (TARC) is a CC chemokine which potentially plays a role via a paracrine mechanism in the development of allergic respiratory diseases. Objectives : The objective of this study is to investigate the effect of Ephedrae Herba Herbal Acupuncture Solution(EHS) on the secretion of TARC of human bronchial epithelial cell. Methods : Enzyme-linked immunosorbent assay (ELISA) was performed to detect the secretion of TARC. The cytotoxicity was measured by MTT assay. Results : EHS significantly inhibited the secretion of TARC with a dose-dependant manner. The effective dosage did not have the cytotoxicity on human bronchial epithelial cell. Conclusion : Results of our study imply that EHS would play an important role in modulation of TARC in human bronchial epithelial cells by MTT assay.

Keywords