한국임상수의학회지 (Journal of Veterinary Clinics)

  • 제22권2호
  • /
  • Pages.119-124
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  • 2005
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  • 1598-298X(pISSN)
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  • 2384-0749(eISSN)
한국임상수의학회 (The Korean Society of Veterinary Clinics)
권호 표지

신동맥색전술과 신우경화술을 이용한 비글견의 실험적 수신증 치료

Treatment of Experimental Hydronephrosis Using Renal Artery Embolization and Sclerotherapy in Beagle Dogs

  • Chang Dong-woo (College of Veterinary Medicine, Chungbuk National University) ;
  • Lee Young-won (College of Veterinary Medicine, Chungnam National University) ;
  • Shin Sang-tae (College of Veterinary Medicine, Chungnam National University)
  • 발행 : 2005.06.01
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초록

This study was performed to validate the procedure of transarterial embolization of the renal artery (TAE-RA) and sclerotherapy of renal pelvis using iohexol-ethanol solution in dogs with unilateral experimental hydronephrosis. Experimental hydronephrosis was induced by unilateral ureter ligation for 20 days in five Beagle dogs. Renal artery embolization with iohexol-ethanol solution was performed using selective catheterization technique in the hydronephrotic kidney and sclerotherapy was done by injection of the iohexol-ethanol solution through percutaneously placed pig-tail catheter. EKG, $SpO_2$ body temperature, pulse, and respiratory rate were within normal ranges during procedures. Average pure ethanol dose for renal artery embolization was $1.1\pm0.3ml/kg$. Renal artery embolization was confirmed by the detection of no blood flow signal at the interlobar and arcuate artery using color Doppler ultrasonography. There were no dogs expired after TAE-RA and sclerotherapy and no side effects associated with regurgitation of iohexol-ethanol solution. The value of BUN, creatinine, ALT, AST, Ca, P in five dogs were within normal range during the experiment period. Ultrasonographically, the mean longitudinal and transverse length and the depth of the embolized kidney significantly decreased at 28 days after TAE-RA. We may conclude that TAE-RA and sclerotherapy with iohexol-ethanol solution is an effective methods for the treatment of unilateral hydronephrosis in dogs.

키워드

참고문헌

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