대한의생명과학회지 (Biomedical Science Letters)
- 제11권2호
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- Pages.103-108
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- 2005
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- 1738-3226(pISSN)
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- 2288-7415(eISSN)
Cellular DNA Repair of Oxidative Deoxyribose Damage by Mammalian Long-Patch Base Excision Repair
- Sung Jung-Suk (Department of Biology, Dongguk University) ;
- Son Mi-Young (Department of Biology, Dongguk University)
- 발행 : 2005.06.01
초록
2-Deoxyribonolactone (dL) arises as a major DNA damage induced by a variety of agents, involving free radical attack and oxidation of C1'-deoxyribose in DNA. We investigated whether dL lesions can be repaired in mammalian cells and the mechanisms underlying the role of DNA polymerase