Effects of SaMulTangGamibang(SMTG) on the Inflammatory Reactions

사물탕가미방이 염증치료 및 예방에 미치는 영향에 대한 연구

  • 윤찬호 (대전대학교 한의과대학 안이비인후피부과) ;
  • 노석선 (대전대학교 한의과대학 안이비인후피부과)
  • Published : 20041200

Abstract

This study was carried out to investigate the effects SMTG on the skin inflammatory reactions. Among the herbal ingredients of SMTG, ethanol extracts of Paeoniae obovata Radix and Acanthopanacis Cortex showed potent radical scavenging activity, more than 90$\%$ at a concnentration of 0.01$\%$, tested by DPPH(1,l-diphenyl-2-picryl-hyrazyl) method. And ethanol extract of Saururi Herba Seu Rhizoma inhibited the lipopolysaccharide-induced release of nitric oxide(NO), 94$\%$ at 50 ㎍/㎖, by the macrophage RAW 246.7 cells. In addition, the ethanol extract of Acanthopanacis Cortex showed antibacterial activities on Staphylococcus aureus that was reported to cause impetigo and atopic disease. Taken together, I expect that SMTG may be used as a drug for treatment on skin inflammation.

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