Korean Journal of Head & Neck Oncology (대한두경부종양학회지)

The Korean Society for Head and Neck Oncology (대한두경부종양학회)
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Risk Factors of Nodal Metastasis in Salivary Gland Cancer

타액선 악성종양의 경부 림프절 전이의 위험 요소

  • Lee Si-Hyung (Department of Otolaryngology, University of Ulsan College of Medicine) ;
  • Nam Soon-Yuhl (Department of Otolaryngology, University of Ulsan College of Medicine) ;
  • Choi Seung-Ho (Department of Otolaryngology, University of Ulsan College of Medicine) ;
  • Park Jung-Je (Department of Otolaryngology, University of Ulsan College of Medicine) ;
  • Kim Chan-Jong (Department of Otolaryngology, University of Ulsan College of Medicine) ;
  • Kang Woo-Seok (Department of Otolaryngology, University of Ulsan College of Medicine) ;
  • Kim Sang-Yoon (Department of Otolaryngology, University of Ulsan College of Medicine)
  • 이시형 (울산대학교 의과대학 서울아산병원 이비인후과학교실) ;
  • 남순열 (울산대학교 의과대학 서울아산병원 이비인후과학교실) ;
  • 최승호 (울산대학교 의과대학 서울아산병원 이비인후과학교실) ;
  • 박정제 (울산대학교 의과대학 서울아산병원 이비인후과학교실) ;
  • 김찬종 (울산대학교 의과대학 서울아산병원 이비인후과학교실) ;
  • 강우석 (울산대학교 의과대학 서울아산병원 이비인후과학교실) ;
  • 김상윤 (울산대학교 의과대학 서울아산병원 이비인후과학교실)
  • Published : 2004.05.01
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Abstract

Background and Objectives: Nodal metastasis is one of the prognostic factors in salivary gland cancer. The purpose of this study is to identify risk factors of nodal metastasis considered as a predictor of poor prognosis in patients with salivary gland cancer. Material and Methods: The authors retrospectively studied 82 patients with salivary gland cancer who underwent surgery from 1992 to 2002. We analyzed age, sex, tumor size, histologic type and 5-year survival rate to compare patients with and without nodal metastasis. Results: Mean age was 55.4 years, with a male-female ratio of 1 : 1.28. The overall 5-year survival rate was 85.5%. Among the 82 patients, 14 patients had nodal metastasis. There was no nodal metastasis in low grade malignancy. In patients without nodal metastasis, mean age was 52.5 years and the overall 5-year survival rate was 94.2%. In patients with nodal metastasis, mean age was 69.4 years and the overall 5-year survival rate was 42.9%. In patients with less advanced cancer (T1-T2 stage), the nodal metastasis was 7.5% and with advanced cancer (T3-T4 stage), 33.3%. Conclusion: Nodal metastasis significantly decreases survival in patients with salivary gland malignancy. High grade malignancy, large tumor size and old age are important risk factors of nodal metastasis. Nodal metastasis is more common in submandibular gland cancer compared with parotid gland cancer.

Keywords

References

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