근위축성 측삭경화증의 진단에 있어서 전기진단학적 검사

Electrophysiological Studies in the Diagnosis of Amyotrophic Lateral Sclerosis

  • 이동국 (대구가톨릭대학교 의과대학 신경과학교실)
  • Lee, Dong Kuck (Department of Neurology, School of Medicine, Catholic University of Daegu)
  • 발행 : 2004.05.31

초록

Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disorder that primarily affects motor neurons. The characteristic features of this devastating disorder are the simultaneous presence of upper and lower motor neuron (LMN) signs with progression from one region of the neuraxis to the next and eventual death, typically from respiratory compromise. Electrophysiological studies are an indispensible part of the ALS evaluation, especially serving as an extension of the clinical examination, and most useful in identifying LMN dysfunction. Not only may electrodiagnostic studies reveal characteristic changes in those regions clinically manifesting signs, but it also serves to disclose asymptomatic areas of involvement.

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