Journal of Haehwa Medicine (혜화의학회지)

Research Institute of Korean Medicine (대전대학교 한의학연구소)
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Studies of SipIMiGwanJungTang that get weight, hematology, biochemistry change by Wistar rat's aging

십이미관중탕(十二味寬中湯)이 Wister rat의 노화에 따른 변화에 미치는 실험적(實驗的) 고찰(考察)

  • Choi, Ye-Won (Dept. of Sasang Constitutional Medicine, College of Oriental Medicine, Daejeon Univ.) ;
  • Anh, Taek-Won (Dept. of Sasang Constitutional Medicine, College of Oriental Medicine, Daejeon Univ.)
  • 최예원 (대전대학교 한의과대학 사상체질의학교실) ;
  • 안택원 (대전대학교 한의과대학 사상체질의학교실)
  • Accepted : 2004.10.14
  • Published : 2004.12.30
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Abstract

Administrating PalMoolGoonJaTang and SipIMiGwanJungTang to 40-weeks-(old Wistar rat for 10 weeks so, I researched into weight change, weight change of internal organ, and hemtological and serological changews. Then I got these conclusions. 1. Observed gain in weight than control group form of SipIMiGwanJungTang to aged Wistar rat. 2. Is thought to promote activation of living body action gaining intestine weight along with gain in weight. 3. Displayed decrease of MDA's content of serum than control group form of SipIMiGwan JungTang to aged Wistar rat. 4. Change that is Wistar rat's hematological value by aging according to 10, 30, 50 week WBC, RBC, Hgb, monocytes, eosinophil etc. increase, and HCT, PLT etc. showed tendency that decrease according to old-week, and observed improvement that is hematological value than control group form of SipIMiGwanJungTang 5. Change that is Wistar rat's biochemical value by aging was measured highest in 50 week because ALT, AST, BUN, CRN, T-bili., T-chol., TG, TP, ALB, A/G, P etc. increase according to 10, 30, 50 week, and observed improvement that is biochemical value than control group form of SipIMiGwanJungTang As those results, PalmoolGoonJaTang and SipIMiGwanJungTang are effective against dacline of physical function as aging. Moreover, considered to the serogical results, SipIMiGwanJungTang is much more effective than the other.

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