Journal of Haehwa Medicine (혜화의학회지)
- Volume 13 Issue 2
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- Pages.109-122
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- 2004
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- 2586-3002(pISSN)
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- 2586-3347(eISSN)
Study on the Effect of CSDDT on Hyperlipidemia
정신도담탕(精神導痰湯)이 식이성(食餌性) 고지혈증(高脂血症) 동물(動物) 병태(病態)에 미치는 영향(影響)
- Lee, Won-Gu (Dept. of internal Medicine, Collage of Oriental Medicine, Daejeon Univ.) ;
- Lee, Yong-Gu (Dept. of internal Medicine, Collage of Oriental Medicine, Daejeon Univ.) ;
- Namgung, Uk (Dept. of Neurophysiology, Collage of Oriental Medicine, Daejeon Univ.) ;
- Kim, Dong-Hee (Dept. of Pathology, Collage of Oriental Medicine, Daejeon Univ.)
- 이원구 (대전대학교 한의과대학부속한방병원 내과학교실) ;
- 이용구 (대전대학교 한의과대학부속한방병원 내과학교실) ;
- 남궁욱 (대전대학교 신경생리학교실) ;
- 김동희 (대전대학교 한의과대학 병리학교실)
- Accepted : 2004.10.14
- Published : 2004.12.30
Abstract
As a long-term goal for the development of new prescriptions for hyperlipidemia, Cheungsimdodamtang(CSDDT) was examined in the present study using a rat model in which the hyperlipidemia was induced. The major parameters related to lipid metabolism were investigated and the key findings are summarized below. 1. CSDDT-treated animal group showed only a 4.5% body weight increase compared to normal animal group whereas hyper- lipidemia-induced control group increased body weight by 13.6% compared to normal animals. 2. CSDDT-induced animal group showed a significant decrease in cholesterol levels beginning one week after CSDDT treatment, compared to hyperlipidemia-induced control group. 3. Total cholesterol levels in CSDDT-treated animal group were significantly decreased compared to the hyperlipidemia-induced control group. 4. Glucose levels in CSDDT-treated animal group were significantly decreased compared to the hyperlipidemia-induced control group. 5. Triglyceride levels in CSDDT-treated animal group were significantly decreased compared to the hyperlipidemia-induced control group. 6. SGOT and SGPT levels in CSDDT-treated animal group were significantly decreased compared to the hyperlipidemia-induced control group. 7. HDL-cholesterol levels were significantly increased in CSDDT -treated animal group compared to the hypeiIipidemia-induced control group. 8. LDL-cholesterol levels were significantly decreased in CSDDT-treated animal group compared to the hyperlipidemia-induced control group.
Keywords