Antimicrobial Effect of Puerariae thunbergiana Extracts against Oral Microorganism

칡 추출물의 구강미생물에 대한 항균효과

  • Lee, Hyun-Ok (Department of Dental Hygiene, Wonkwang Health Science College) ;
  • Kim, Chang-Hee (Department of Dental Hygiene, Shinsung College) ;
  • Lim, Jin-A (Department of Herbal Resources, Professional Graduate School of Oriental Medicine and Institute of Basic Natural Sciences, Wonkwang University) ;
  • Lee, Mi-Hee (Department of Herbal Resources, Professional Graduate School of Oriental Medicine and Institute of Basic Natural Sciences, Wonkwang University) ;
  • Baek, Seung-Hwa (Department of Herbal Resources, Professional Graduate School of Oriental Medicine and Institute of Basic Natural Sciences, Wonkwang University)
  • 이현옥 (원광보건대학 치위생과) ;
  • 김창희 (신성대학 치위생과) ;
  • 임진아 (원광대학교 한의학전문대학원 한약자원개발학과) ;
  • 이미희 (원광대학교 한의학전문대학원 한약자원개발학과) ;
  • 백승환 (원광대학교 한의학전문대학원 한약자원개발학과)
  • Received : 2004.06.09
  • Accepted : 2004.06.16
  • Published : 2004.06.30

Abstract

In the current research for natural products with antimicrobial effects, various extracts of Puerariae thunbergiana and isoflavones against microorganisms were evaluated in terms of the minimum inhibitory concentrations (MIC). In general, Candida albicans was stronger antimicrobial activity than the other microorganisms such as Streptococcus mutans, Staphylococcus epidermidis, and Staphylococcus aureus. The maximum activity was exhibited by methanol extract of the leaves of Puerariae thunbergiana Beth. against Candida albicans(MIC, $400{\mu}g/mL$). These results suggest that methanol extract of Puerariae thunbergiana has a potential antimicrobial activity.

Keywords