Journal of Preventive Medicine and Public Health

The Korean Society for Preventive Medicine (대한예방의학회)
권호 표지

Association of Dietary Factors with Cognitive Impairment in Older Women

여성 노인의 식이요인과 인지기능 감퇴의 관련성

  • Kim, Jin-Hee (Department of Preventive Medicine and Public Health, Ajou University School of Medicine) ;
  • Han, Geun-Shik (Department of Information System Engineering, College of Information Sciences, Hanshin University) ;
  • Lee, Yun-Hwan (Department of Preventive Medicine and Public Health, Ajou University School of Medicine)
  • 김진희 (아주대학교 의과대학 예방의학교실) ;
  • 한근식 (한신대학교 정보과학대학 정보시스템공학과) ;
  • 이윤환 (아주대학교 의과대학 예방의학교실)
  • Published : 2004.06.01
Download PDF
⟨ Previous Next ⟩

Abstract

Objective : To examine the association between dietary factors and cognitive impairment in older Korean women living in the community. Methods : Wave 2 data, from the Suwon Longitudinal Aging Study (SLAS), of 365 women aged 65 years or over, were used. The Korean version of the 30-point Mini-Mental State Examination (MMSE-K) was used to assess cognitive impairment (score$\geq$19). Dietary habits and frequencies of food group consumption were also examined. Results : A total of 67 women (18.4%) were found to be cognitively impaired. In bivariate analyses, nondietary factors, such as age, marital status, education, income, self-rated health, depression, emotional support, social activity, exercise, and dietary factors, such as self-rated nutritional status, frequency of beans and bean products and milk and dairy products consumption were associated with cognitive impairment. In the multivariate analysis, a higher frequency ($\geq$1 vs. <1 time/day) of beans and bean products (OR=0.48, 95% CI: 0.23-0.99) and milk and dairy products (OR=0.25, 95% CI: 0.10-0.61) consumption was inversely associated with cognitive impairment, after adjustment for non-dietary factors. Conclusion : These results suggest that dietary factors may play a significant role in cognitive impairment of older Korean women.

Keywords

References

  1. 통계청 2003 고령자통계 통계청; 2003
  2. 노재규. 신경질환. 의학교육연수원 편. 노인의학. 서울대학교출판부; 1997, (568-580쪽)
  3. Nam Koong K, Lee HS, Yoo KJ. Diagnosis and treatment of dementia. J Korea Gerontol Soc 1993; 13: 168-177 (Korean)
  4. Zarit SH, Zarit JM. Mental disorders in older people. Fundamentals of assessment and treatment. New York Guilford Press; 1998
  5. Lee LH, Kang SA, Parle JS, Kim JH, Jung IK,Park YJ, Lee JE. Relationship between general characteristics and cognitive function in Korean elderly people. J Asian Reg Assoc Home Econ 2000; 7: 172-177
  6. Kim JH, Kang SA, Ahn HS, Jung IK, Lee LH. Effect of education level on depression and dietary intakes among elderly Korean women. J Asian Reg Assoc Home Econ 1997; 4:47-55
  7. Kim JH, Kang SA, Ahn HS, Jung IK, Lee LH. Relationship between cognitive function and dietary pattems in Korean elderly Women. Korean Nutr Soc 1998; 31: 1457-1467 (Korean)
  8. Kang HK. Aging (II) analysis of pathway among factors affecting food intake and cognitive function of the aged. Korean J DietCult 2002; 17: 289-298 (Korean)
  9. Goodwin JS, Goodwin JM, Garry PJ. Association between nutritional status and cognitive functioning in a healthy elderly population JAMA 1983; 249: 2917-2921
  10. Riggs KM, Ill AS, Tucker K, Rush D. Relations of vitamin B-12, vitamin B-6, folate, and homocysteine to cognitive performance in the normative Ageing Study. Am J Clin Nutr 1996; 63: 306-314 https://doi.org/10.1093/ajcn/63.3.306
  11. 한국보건산업진흥원. 2001년도 국민건강. 영양조사: 영양조사부문. 한국보건산업진흥원. 2002
  12. Cho MJ, Bae JN, Suh GR,Hahm BJ,Kim JK Lee DW, Kang :MH. Va1idation of geriatric depression scale, Korean version (GDS) in the assessment of DSM-III-R major depression. J Korean Neuropsychiatr Assoc 1999; 38: 48-63 (Korean)
  13. Kwon YC, Park JH. Korean version of mini-mental state examination (MMSE-K)part I: development of the test for the elderly. J Korean Neuropsychiatr Assoc 1989; 28: 125-135 (Korean)
  14. Park JH, Kwon YC. Standardization of Korean version of the mini-mental state examination (MMSE-K) for use in the elderly. Part II. Diagnostic validity. J Korean Neuropsychiatr Assoc 1989; 28 508-513 (Korean)
  15. SPSS. SPSS Base 10.0 User's Guide SPSS, Inc. 1999
  16. 변용찬. 치매관리 Mapping 개발 연구. 한국보건사회연구원. 1997
  17. Kim DH, Na DL, Yeon BK, Kang YW, Min KB, Lee SH, Lee SS, Lee MR, Pyo OJ, Park CB, Kim SM, Bae SS. Prevalence of dementia in the elderly of an urban community in Koreι Korean J Prev Med 1999; 32: 306-316 (Korean)
  18. Park SO, Han SS , Ko YS, Kim YJ, Lee HS, Kang NE, Lee JH, Kim WK, Kim SH. A study on the relations between dietary intake and cognitive function in the elderly. Korean I Diet Cult 1992; 7 149-155 (Korean)
  19. Lee LH. Associations between dietary intake and health status in Korean elderly popuation. Korean Nutr Soc 2002; 35 124-136 (Korean)
  20. Fraser GE, Singh PN, Bennett H. Varia bles associated with cognitive function in elderly California Seventh-day Adven tists. Am J Epidemiol 1996; 143: 1181-1190 https://doi.org/10.1093/oxfordjournals.aje.a008705
  21. Gifford DR, Holloway RG, Vickrey BG. Systemic review of clinical prediction rules for neuroimaging in the evaluation of dementia. Arch Intern Med 2000; 160: 2855-2862 https://doi.org/10.1001/archinte.160.18.2855
  22. Lee YS, Kim HK. Nutritional status and cognitive status of the elderly using public health center in Ulsan. Korean Nutr Soc 2002; 35: 1070-1080 (Korean)
  23. Yoon SJ, Lee YH, Son TY, Oh HJ, Han GS, Kim KH. Factors associated with dementia and depressive symptoms in older persons living in the community. J Korea Gerontol Soc 2002; 21: 59-73 (Korean)
  24. Oh BH, Kim HS, Kim JH, Cho HS, Cho KH Cho HS, Yoo KJ. Epidemiologic study of cognitive impairment and depressive symptoms of the elderly in a Korean rural community. J Korean Geriatr Psychiatry 1998; 2: 176-186 (Korean)
  25. Cody V. Middleton EJr, Harborne JB, eds. Plant flavonoids in biology and medicine. New York: Alan R Liss, Inc.; 1986
  26. Hertog MGL, Hollman PCH，Katan MB. Content of potentially anticarcinogenic flavonoids of 28 vegetables and 9 fruits commonly consumed in the Netherlands. J Agric Food Chem 1992; 40: 2379-2383 https://doi.org/10.1021/jf00024a011
  27. Harborne JB. The flavonoids. Cambridge, UK: Chapman & Hall;1994
  28. Sanders TAB, Dean TS, Grainger D, Miller GJ, Wiseman H. Moderate intake of intact soy protein rich in isoflavone, compared with ethanol-extracted soy potein increase HDL but do not influence transforming growth factor B1 concentrations and heart disease in healthy subjects Am J Clin Nutr 2002; 76:373-377
  29. Knekt P, Kumpulainen J, Jarvinen R, Rissanen H，Heliovaara M, Reunanen A, Hakulinen T, Aromaa A. Flavonoid intake and risk of chronic diseases. Am J Clin Nutr 2002; 76: 560-568 https://doi.org/10.1093/ajcn/76.3.560
  30. Jenkins DJA, Kendall CWC, Jackson CJC, Connelly PW, Parker T, Faulkner D, Vidgen E, Cunnane SC, Leiter LA, Josse RG. Effects of high- and low-isoflavone soyfoods on blood lipids, oxidized LDL, homocysteine，and blood pressure in hyperlipidemic men and women. Am J Clin Nutr 2002; 76: 365-372 https://doi.org/10.1093/ajcn/76.2.365
  31. Lori C, Neil CB, Kenneth DRS, Stephen B. Genistein daidzein, and their $\beta$glycoside conjugates: antitumor isoflavones in soybean foods from American and Asian diets. J Agric Food Chem 1993;41: 1961-1967 https://doi.org/10.1021/jf00035a027
  32. Hutchins AM, Lampe JW， Martini MC, Cambell DR, Slavin JL. Vegetables, fruits and legumes: Effect on urinary isoflavonoid phytoestrogen and lignan excretion. J I Am Diet Assoc 1995; 95: 769 774
  33. Adlercreutz H. Lignans and isoflavonoids: epidemiology and a possible role in prevention of cancer, In: Kumpulainen JT, Salonen JT, eds. Natural antioxidants and cancer prevention. Cambridge, UK: The Royal Society of Chemistry; 1996
  34. Anderson JJ, Garner SC. The effects of phytoestrogens on bone. Nutr Res 1997; 17: 1617-1632 https://doi.org/10.1016/S0271-5317(97)00156-5
  35. Duffy R, Wiseman H, File SE. Improved cognitive function in postmenopausal women after 12 weeks of containing of a soya extract containing isoflavones. Pharmacol Biochem Behav 2003; 75 721-729
  36. Kuiper GG, Lemmen JG, Carlsson B, Corton JC, Safe SH, van der Saag PT, van der Burg B, Gustafsson JA.Interaction of estrogenic chemicals and phytoestrogens with estrogen receptor beta. Endocrinology 1998; 139: 4252-4263 https://doi.org/10.1210/en.139.10.4252
  37. Pike AC, Brzozowski AM, Hubbard RE, Bonn T, Thorsell AG, Engstrom O, Ljunggren J, Gustafsson JA, Carlquist M. Structure of the ligand-binding domain of oestrogen receptor beta in the presence of a partial agonist and a full antagonist. EMBOJ1999; 18: 4608 -4618 https://doi.org/10.1093/emboj/18.17.4608
  38. Gundlah C, Koharua SG, Mirkes SJ, Garyfallou VT, Urbanski HF, Bethea CL. Distribution of estrogen receptor beta (ERbet) mRNA in hypothalamus，midbrain and temporal lobe of spayed macaque: continued expression with hormone replacement. Brain Res Mol Brain Res 2000; 76: 191-204 https://doi.org/10.1016/S0006-8993(99)02475-0
  39. Osterlund MK, Gustafsson JA, Keller E, Hurd YL. Estrogen recept $\beta$ (ER$\beta$) messenger ribonucleic acid (mRNA) expression within the human forebrain: distinct distribution psttern to ERa mRNA. J Clin Endφcrinol Metab 2000; 85: 3840-3846 https://doi.org/10.1210/jc.85.10.3840
  40. McEwen BS. Invited review: estrogens effects on the brain: multiple sites and molecular mechanisms. J Appl Physiol 2001; 91: 2785-2801
  41. Pan Y, Anthony M, Clarkson TB Effect of estradiol and soy phytoestrogens on choline acetyltransferase and nerve growth factor mRNAs in the frontal cortex and hipocampus of female rats. Proc Soc Exp Biol Med 1999; 221: 118-125
  42. Pan Y, Anthony M, Clarkson TB. Evi dence for up-regulation of brain-derived neurotphic factor mRNA by soy phytoestrogens in the frontal cortex of retired breeder female rats. Neurosic Lett 1999; 261: 17-20 https://doi.org/10.1016/S0304-3940(98)00994-X
  43. Nilsen J, Brinton RD. Impact of proge stins on estradiol potentiation of the glutamate calcium response. Neuroreport 2002; 13: 825-830 https://doi.org/10.1097/00001756-200205070-00018
  44. Toran-A1lerand CD, Singh M, Setalo G Jr. Novel mechanisms of estrogen action in the brain: newplayers in an old story. Frort Neuroendocrinol 1999; 20: 97-121 https://doi.org/10.1006/frne.1999.0177
  45. Kelly MJ, Levin ER. Rapid actions of plasma membrane estrogen receptors. Trends Endocrinol Metab 2001; 12: 152-156 https://doi.org/10.1016/S1043-2760(01)00377-0
  46. Kang NE. A study on the influence of aging and nutrition on the cognitive function by the blood glucose level among elderly Korean. Ewha Woman's University Doctoral Thesis. 1993 (Korean)
  47. 영양학의 최신정보 제7차 개정판. 한국영양학회, 한국국제생명과학회; 1998, (507-508쪽)
  48. Horwath CC. Validity of a short food frequency questionnaire for estimating nutrient intake in elderly people. British J Nutr 1993; 70:3-14 https://doi.org/10.1079/BJN19930100
  49. Potosky AL, Block G, Hartman AM. The apparent validity of diet questionnaires is influenced by number of diet-record days used for comparison. J Am Diet Assoc 1990; 90:810-813
  50. Horwath CC, Worsley A. Assessment of the validity of a food frequency question naire as a measure of food use by comparison with direct observation of domestic food stores. Am J Epidemiol 1990; 131: 1059-1067 https://doi.org/10.1093/oxfordjournals.aje.a115597
  51. Won HS, Kim WY. Development and validation of a semi-quantitative food frequency questionnaire to evaluate nutri tional status of Korean elderly Korean Nutr Soc 2000; 33: 314-323 (Korean)
  52. Block G. A review of validations of dietary assessment methods. Am J Epidemiol 1982; 115: 492-505 https://doi.org/10.1093/oxfordjournals.aje.a113331