Association between Alcohol Drinking and Cardiovascular disease Mortality and All-cause Mortality - Kangwha Cohort Study -

음주와 순환기계질환 사망 및 전체사망과의 관련성

  • Yi, Sang-Wook (Department of Preventive Medicine and Public Health, Kwandong University College of Medicine) ;
  • Yoo, Sang-Hyun (Department of Public Health, The Graduate School, Yonsei University) ;
  • Sull, Jae-Woong (Department of Public Health, The Graduate School, Yonsei University) ;
  • Ohrr, Hee-Choul (Department of Preventive Medicine and Public Health, Yonsei University College of Medicine)
  • 이상욱 (관동대학교 의과대학 예방의학교실) ;
  • 유상현 (연세대학교 대학원 보건학과) ;
  • 설재웅 (연세대학교 대학원 보건학과) ;
  • 오희철 (연세대학교 의과대학 예방의학교실)
  • Published : 2004.06.01

Abstract

Objectives : This study sought to examine relationships between alcohol drinking and cardiovascular disease mortality and all-cause mortality. Methods : From March 1985 through December 1999, 2,696 males and 3,595 females aged 55 or over as of 1985 were followed up for their mortality until 31 December 1999. We calculated the mortality risk ratios by level of alcohol consumption. Among the drinker, the level of alcohol consumption was calculated by the frequency of alcohol comsumption and the type of alcohol. Cox proportional hazard model was used to adjust for confounding factors. Results : Among males, compared to abstainer, heavy drinker had significantly higher mortality in all cause(Risk ratio=1.35), cardiovascular disease(Risk ratio=1.52) and cerebrovascular disease(Risk ratio =1.66). Although not significant, moderate drinker had lower ischemic heart disease mortality(Risk ratio =0.38). Among females, there was no statistically significant association between alcohol comsumption and mortality. Conclusion : The results of this study suggest that alcohol drinking has harmful effect on all-cause mortality, cardiovascular disease mortality and cerebrovascular disease mortality among males, especially in heavy drinker among males. Minimal evidence on protective effect for cardiovascular disease mortality in low or moderate drinker is observed.

Keywords

References

  1. 보건복지부. 1998 년도 국민건강 영양조사-보건의식행태조사. 1999
  2. 고경환 순수얄코올 소비량의 추계와 국제비교. 보건복지포럼 2000; 6: 77-86
  3. Tsugane S, Fahey MT, Sasaki S, Baba S. Alcohol consumption and all-cause and cancer mortality among middle-aged Japanese men: seven-year follow-up of the JPHC study Cohort I. Japan Public Health Center. Am J Epidemiol. 1999; 150(11) 1201-1207
  4. Rehm J, Greenfield TK, Rogers JD Average volume of alcohol consumption, patterns of drinking, and all-cause mortality: results from the US National Alcohol Survey. Am J Epidemiol. 2001; 153(1): 64-71
  5. Hart CL, Smith GD, Hole DJ, Hawthorne VM. Alcohol consumption and mortality from all causes, coronary heart disease, and stroke: results from a prospective cohort study of scottish men with 21 years of follow up. BMJ. 1999; 318 (7200): 1725-1729 https://doi.org/10.1136/bmj.318.7200.1725
  6. Oh HC,Nam J,Lee SH.A Cohort study on the relationship between pesticide use and mortality, and cancer mortality. Korean J Prev Med 1991; 24(3): 390-399 (Korean)
  7. Kim IS, Ohrr H, Jee SJ, Kim H, Lee Y. Smoking and Total Mortality: Kangwha Cohort Study, 6-year Follow-up. Yonsei Med J 1993; 34(3): 212-222 https://doi.org/10.3349/ymj.1993.34.3.212
  8. Sull JW, Yi SW, Sohn TY, Jee SH, Nam CM, Ohrr H. Pesticides and cancer Incidence. Korean J Prev Med 2002; 35(1) 24-32(Korean)
  9. 대한주류공업협회지. 대한주류공업협회. 1986
  10. Willett W. Nutritional epidemiology. NewYork, NY: Oxford University Press, 1990
  11. Willett WC, Sampson L, Browne ML, etal. The use of a self-administered question -naire to assess diet four years in the past. Am J Epidemiol 1988; 27: 188-199
  12. Hartwell DL, Henry CJ. Comparison of a self-administered quantitative food amount frequency questionnaire with 4day estimated food records. Int J Food Sci Nutr 2001; 52(2): 151-159 https://doi.org/10.1080/713671770
  13. Chaikelson JS, Arbuckle TY, Lapidus S, Gold DP. Measurement of lifetime al cohol consumption. J Stud Alcohol 1994; 55(2): 133-140 https://doi.org/10.15288/jsa.1994.55.133
  14. Flegal KM. Agreement between two dietary methods in reported intake of beer, wine and liquor. J Stud Alcohol 1991; 52(2): 174-179 https://doi.org/10.15288/jsa.1991.52.174
  15. Plant M, Heavy drinking by young British women gives cause for concern. BMJ. 2001;323(7322):1183
  16. Hillbom M, Numminen H, Juvela S. Recent heavy drinking of alcohol and embolic stroke. Stroke 1999; 30(11) 2307-2312
  17. Choi EY, Im YS, KimKN, Park CY,Kim HJ, Cho B, Lee S, Yoo T, Huh BY. Alcohol habits in Korea. J Korean Acad Fam Med 1988; 19: 858-869 (korean)
  18. Fillmore KM, GoldingJM, Graves KL, Kniep S, Leino EV, Romels A, Shoe maker C, Ager CR, Allebeck P, Ferrer HP.Alc:ohol consumption and mortality I. Characteristics of drinking group, Addiction 1998; 93(2): 183-203 https://doi.org/10.1046/j.1360-0443.1998.9321834.x
  19. Djousse L, Ellison RC, Beiser A, Scaramucci A, D'Agostino RB, Wolf PA. Alcohol consumption and risk of ische mic stroke: The Framingham Study stroke: The Framingham Study. Stroke 2002; 33(4): 907-912 https://doi.org/10.1161/hs0402.105245
  20. Hammar N, Romelsjo A, Alfredsson L. Alfredsson L. Alcohol consumption, drinking pattern and acute myocardial infarction: a case referent study based on the Swedish Twin Register. J Intern Med 1997; 241 125-131
  21. Kauhanen J, Kaplan GA, Goldberg DE, Salonen JT. Beer binging and mortality: results from the Kuopio Ischaemic Heart Disease Risk Factor Study,a prospective population based study. BMJ 1997; 315 846-851
  22. Murray RP, Counett JE, Tyas SL, Bond R, Ekuma O, Silversides CK, Barnes GE. Alcohol volume, drinking pattern, and cardiovascilar disease morbidity and mortality: is there a U-shaped function? Am J Epidemiol 2002; 155(3): 242-248 https://doi.org/10.1093/aje/155.3.242
  23. Malyutina S, Bobak M, Kurilovitch S, Gafarov V, Simonova G, Nikitin Y, Marmot M. Relation between heavy and binge drinking and all-cause and cardiovascular mortality in Novosibirsk, Russia: a prospective cohort study. Lancet 2002; 360(9344): 1448-1454 https://doi.org/10.1016/S0140-6736(02)11470-X
  24. Britton A, McKee M. The relation between alcohol and cardiovasculaer disease in Eastem Europe: explalliing the paradox. J Epidemiol Community Health. 2000; 54(5): 328-332 https://doi.org/10.1136/jech.54.5.328
  25. National Statistic Office. 2001 Annual Report on The Cause of Death Statistics. Daejon. 2002(Korean)
  26. Gordon T, Kannel WB. Drinking and mortality. The Framingham Study. Am J Epidemiol 1984; 120(1): 97-107 https://doi.org/10.1093/oxfordjournals.aje.a113879
  27. Reynolds K, Lewis B, Nolen JD, Kinney GL, Sathya B, He J. Alcohol consumption and risk of stroke: a meta-analysis. JAMA 2003; 289(5): 579-588 https://doi.org/10.1001/jama.289.5.579
  28. Plant ML. Women and alcohol: contem and porary and historical perspectives. London: Free Association Books, 1997