Korean Journal of Clinical Laboratory Science (대한임상검사과학회지)
- Volume 36 Issue 1
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- Pages.27-32
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- 2004
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- 1738-3544(pISSN)
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- 2288-1662(eISSN)
Clinical Significance of Immature Reticulocyte as an Early Recovery Indicator after Bone Marrow Transplantation
골수이식 후 미성숙 망상적혈구의 유용성 평가
- Seo, Suk Won (Department of Laboratory Medicine, College of Medicine, University of Ulsan and Asan Medical Center) ;
- Kim, Chun Hee (Department of Laboratory Medicine, College of Medicine, University of Ulsan and Asan Medical Center) ;
- Chi, Hyun Sook (Department of Laboratory Medicine, College of Medicine, University of Ulsan and Asan Medical Center)
- Published : 2004.06.30
Abstract
Bone marrow transplantation(BMT) is widely used as curative means of various malignant and nonmalignant hematologic disorders, and early and accurate determination of engraftment is very important for critical management decisions. Reticulocyte counts performed by automated flow cytometric methods is a good indicator of erythropoietic activity and its evaluation has been proposed as an early predictor of bone marrow regeneration. Some reports highlighted the usefulness of the percentage of highly fluorescent reticulocytes and the sum of highly and medium fluorescent reticulocytes(immature reticulocyte fraction, IRF). In Asan Medical Center, the criteria for engraftment following BMT or PBSCT was defined as the first day of a 3-day trend of absolute neutrophil count(ANC)
Keywords
- Immature reticulocyte fraction(IRF);
- Absolute neutrophil count(ANC);
- Bone marrow transplantation (BMT)