Bilateral Striopallidodentate Salcinosis on CT and MRI : Case Report

양측성 선조-담창-치상액 석회증의 전산화단층촬영과 자기공명영상 소견 : 증례보고

  • Lee Jong Deok (Department of Diagnostic Radiology, Collage of Oriental Medicine, Wonkwang University, Gwangju Oriental medical hospital Wonkwang hospital, Wonkwang University)
  • 이종덕 (원광대학교 한의과대학 진단방사선학과 원광대학교 부속 광주한방병원 원광병원)
  • Published : 2004.04.01

Abstract

Bilateral striopallidodentate calcinosis, popularly referred to as Fahr's disease, is a disorder radiologically characterized by bilateral calcifications of the basal ganglia, thalami, dentate nuclei of the cerebellum, and the white matter of the cerebral hemisphere without serum calcium-phosphorus metabolism and related endocrinologic abnormalities. Intracranial calcifications are easily visible as high-density on CT. On magnetic resonance images, the calcifications exhibit different signal intensities. The differences in signal intensity are thought to be related to the stage of the disease, differences in calcium metabolism, and the volume of the calcium deposit. Based on literature review, I report the case of a 63 year man with bilateral symmetrical calcification in the basal ganglia, dentate nuclei of the cerebellum, and the white matter of the cerebral hemisphere who present a 5 year history of progressive dysarthria associated with left thalamic infarction.

Keywords

References

  1. Neurology v.29 Calcification of the basal ganglia : computerized tomography and clinical correlation Koller WC;Cochran JW;Klawans HL https://doi.org/10.1212/WNL.29.3.328
  2. J Neurol Neurosurg Psychiatry v.44 The significance of the incidental finding of basal ganglia calcification on computed tomography Harrington MG;Macpherson P;McIntosh WB;Allan BF;Bone I
  3. J Neurol v.239 Neurological disorders in 166 patients with basal ganglia calcification : a statistical evaluation Forstl H;Krumm B;Eden S;Kohlmeyer K
  4. Ann Med Psychol v.2 Ossification des capillaries du cerveau Delacour A
  5. Verhandl Phy Med Gesellsch v.6 Beobachtungen und bemerkungen uber hirnkrantheiten Bamberger H
  6. Arch Neurol Neurochir Psychiatr v.1 Eine familial auftrentende from vonolidophrenie mit vontgenologish nachveisbaren symmetrischein Kalkoablagerungenim Geheirn besounders in den Stammganglien Schweiz Fritzsehe R
  7. Mov Disord v.5 no.(Suppl 1) Bilateral striopallidodentate calcinosis: a proposed classification of genetic and secondary causes Manyam BV
  8. Ann Neurol v.31 Bilateral striopallidodentate calcinosis : cerebrospinal fluid, imaging, and electrophysiological studies Manyam BV;Bhatt MH;Moore WD;Devleschoward AB;Anderson DR;Calne DB
  9. J Korean Radiol Soci 25(4) v.25 no.4 Incidense of Basal Ganglia Calcifcation on Brain CT Kim IS;Lim j;Park SH;Kim CY;Bahk YW https://doi.org/10.3348/jkrs.1989.25.4.500
  10. Neurology v.39 Familial idiopathic striopallidodentate calcifications Ellie E;Julien J;Ferrer X https://doi.org/10.1212/WNL.39.3.381
  11. Eur Neurol v.22 Progressive idiopathic stroi-pallido-dentate calcification (Fahr's diseae) with autosomal recessive inheritance ; report of three siblings Smits MG;Gabreels FJM;Thijssen HOM(et al) https://doi.org/10.1159/000115537
  12. In Handbook of Clinical Neurology, Disease of the Basal Ganglia v.6 Calcification of the striopallidodendate system Lwenthal,A.;Bruyn, G. W.;P. J. Vinken;G. W. Bruyn(ed)
  13. Movement disorders in neurology and neuropsychiatry(1st ed) Striopallidodentate calcifications Lowenthal A; De Deyn PP
  14. J Neuropath Exp Neurol v.22 Iron and calcium dysmetabolism in the brain with special predilection fur globus pallidus and cerebellum Neumann MA https://doi.org/10.1097/00005072-196301000-00011
  15. Acta Neuropathol (Berl) v.38 Presence of zinc, aluminium, magnesium in striopallidodentate (SPD) calcifications(Fahr disease): electron probe study Galle p;Escourolle R;Poirier J;Hauw JJ
  16. Handtook of clinical neurology: diseases of the basal ganglia v.6 Calcification of the striopallidodentate system Lowenthal A;Bruyn GW;Vinkin PJ;Bruyn GW(eds)
  17. Neurology v.25 The chemical composition of idiopathic nonarteriosclerotic cerebral calcifications Smeyers-Verbeke J;Michotte Y;Pelsmaeckers J(et al) https://doi.org/10.1212/WNL.25.1.48
  18. Arch Psychiatr Nervenheilkd v.225 Laser spectrographic analysis of the cation content in Fahr syndrome Kozik M;Kulczycki J https://doi.org/10.1007/BF00343397
  19. J Neurol Neurosurg Psychiatry v.23 The influence of a vascular factor on the distribution of symmetrical cerebral calcification Norman RM;Urich R https://doi.org/10.1136/jnnp.23.2.142
  20. Handbook of Clinical Neurology v.19 Calcification of the striopallidodentate system lowenthal A;Bruyn GW;Vinhen PH;GW Bruyn(eds)
  21. J Neurol Neurosurg Psychiatry v.26 The localization of alkaline- phosphatase activity in cerebral blood vessels Bannister RG;Romanul RCA https://doi.org/10.1136/jnnp.26.4.333
  22. Shinkeibyourigaku-kisotorinsyou Fahr's disease Honda E;Tomonaga M;Okeda R;(eds)
  23. Angiology v.40 Microvasculopathy may precede idiopathic cerebral calcifications - case report Gomez CR;Luque A;Horenstein S https://doi.org/10.1177/000331978904000113
  24. J comput Assist Tomogra v.9 no.4 MR imaging in Fahr diseas Scotti G;Sialfa G;Tampieri D;Landoni L
  25. Radiology v.179 High signal intensity in MR images of calcified brain tissue Henkelman RM;Watts JF;Kucharczyk W https://doi.org/10.1148/radiology.179.1.1848714
  26. J Neurol v.241 MRI demonstration and CT correlation of the brain in patients with idiopathic intra cerebral calcification Avrahami E;Cohn DF;Feibel M;Tadmor R https://doi.org/10.1007/BF02033355
  27. J Neurolo Neurosurg Psychiatry v.40 Familial idiopathic cerebral calcification Boller F;Boller M;Gilbert J https://doi.org/10.1136/jnnp.40.3.280
  28. Mov Disord v.13 Functional improvement in a patient with cerebral calcinosis using a biphophonate Loeb JA https://doi.org/10.1002/mds.870130225