Journal of Physiology & Pathology in Korean Medicine (동의생리병리학회지)

The Physiological Society of Korean Medicine and The Society of Pathology in Korean Medicine (대한동의생리학회·한의병리학회)
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Comparative Study of Nitric Oxide Scavenging Effect in Several Herbal Extracts

  • Yoo Yeong Min (Department of Biology, College of Natural Science, Kangwon National University, Department of Oriental Pathology, College of Oriental Medicine, Sangji University) ;
  • Lee Seon Goo (Department of Oriental Pathology, College of Oriental Medicine, Sangji University)
  • Published : 2004.10.01
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Abstract

In this study, we investigated in vitro nitric oxide (NO) scavenging effect on nine herbal extracts using an NO donor S-nitroso-N-acetylpenicillamine (SNAP) compared with vitamin C. All herbal extracts effectively reduced the generation of NO radicals in a dose-dependant manner and over 65% in 10h. Especially, Ephedrae herba, Carthami flos and Lonicerae flos declined over 75% of NO scavenging effect, suggested that the herbal extracts are the powerful free radical scavengers and may be effective in clinical applications.

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