Journal of Physiology & Pathology in Korean Medicine (동의생리병리학회지)

The Physiological Society of Korean Medicine and The Society of Pathology in Korean Medicine (대한동의생리학회·한의병리학회)
권호 표지

Antioxidative and Antifungal Activity of Equisetum arvense L.

쐐뜨기의 항진균 및 항산화 효과

  • Chun Hyun Ja (Department of Natural Science, College of Natural Sciences, Wonkwang University) ;
  • Kim Young Hyun (Department of Natural Science, College of Natural Sciences, Wonkwang University) ;
  • Lee Hong (Department of Natural Science, College of Natural Sciences, Wonkwang University) ;
  • Lee Young Hang (Department of Natural Science, College of Natural Sciences, Wonkwang University) ;
  • Chai Kyu Yun (Department of Natural Science, College of Natural Sciences, Wonkwang University)
  • 천현자 (원광대학교 자연과학대학 자연과학 기술학부) ;
  • 김용현 (원광대학교 자연과학대학 자연과학 기술학부) ;
  • 이홍 (원광대학교 자연과학대학 자연과학 기술학부) ;
  • 이영행 (원광대학교 자연과학대학 자연과학 기술학부) ;
  • 채규윤 (원광대학교 자연과학대학 자연과학 기술학부)
  • Published : 2004.10.01
Download PDF
⟨ Previous Next ⟩

Abstract

We investigated antifungal and antioxidant activity of Equsetum arvense L. The sterile stems of Equsetum arvense L. were extracted with methanol and then fractionated with n-hexane, ethyl acetate, butanol, and water. And their antifungal activities were determined by using paper disk diffusion method and (1. 3)β-glucan synthase inhibitory activity assay, and antioxidant activities were determined by using DPPH method. The ethyl acetate fraction showed antifungal activity on Candidas albacans in both disk diffusion and enzyme assays. This also showed antioxidant activity in DPPH assay. Further fractionation with ethyl acetate fraction was performed to obtain effective fractions. 4, 5, 6 and 7 fractions showed the significant antifungal antivities, and, 4 and 5 fractions showed the strongest antioxidative activity.

Keywords

References

  1. Korean J. Medicinal Crop Sci v.11 no.1 Antioxidant, Antimutagenicity and anticancer activities of extracts from Cirsium japonicum var. ussuriense KITAMURA Lee, H. K.;Kim, J. S.;Kim, N. Y.;Kim, M. J.;Park, S. U.;Yu, C. Y.
  2. Antimicrob. Agents Chemother. v.39 Resistance of Candida species to fluconazole Rex, J. H.;Rinaldi, M. G.;Pfaller, M. A.
  3. Trends in Microbiology v.5 Update on antifungal resistance Klepser, M. E.;Ernst, E. J.;Pfaller, M. A.
  4. Trends in Microbiology v.3 The fungal cell wall as a drug target Georgopapadakou, N. H.;Tkacz, J. S.
  5. Annu. Rev. Microbiol. v.48 Antibiotics that inhibit fungal cell wall development Debono, M.;Gordee, R. S.
  6. Microbiology v.140 Characterization of (1,3)-${\beta}$-glucan synthase in Candida albicans: microsomal assay from the yeast or mycelial morphological forms and a permeabilized whole-cell assay Frost, D. J.;Brandt, K.;Capobianco, J.;Goldman, R.
  7. J. Antibiot. v.53 Arborcandins A, B, C, D, E and F, Novel (1, 3)${\beta}$-glucan synthase inhibitors: production and biological activity Ohyama, T.;Kurihara, Y.;Ono, Y.;Ishikawa, T.;Miyakoshi, S.;Hamano, K.;Arai, M.;Suzuki, T.;Igari, H.;Suzuki, Y.;Inukai, M.
  8. The Korean Journal of Mycology v.25 버섯중 항균 활성물질의 개발-버섯 중의 식물병원성 곰팡이에 대한 항균활성 물질 검색 민지영;김은미;민태진
  9. 대한식물도감 이창복
  10. 중약대사전 소학관(편)
  11. Khim. Prir. Soedin v.3 Flavonoid glycosides from sporogenous stems of Equisetum arvense Syrchina, A. I.;Gorokhova, V. G.;Tyukavkina, N. A.;Bebkin, V. A.;Voronkov, M. G.
  12. Khim. Prir.Soedin v.3 5-Glycoside of Equisetum arvense flavones Syrchina, A. I.;Zapesochnaya, G. G.;Tyukavkina, N. A.;Voronkov, M. G.
  13. E. Merck's Johnesber v.50 Pharmacological tria with some domestic plants Kreimair, H.
  14. Agent for treatment of urolithiasis. U.S.S.R. SU 1,324,669(CLA-61K35/78) Lyubartseva, A. A.;Socolova, V. E.;Kolesnikov, D. G.;Shengur, V. F.
  15. Biogenic silanol complexes from Equisetum arvense. Fr. Demande FR 0,523(CLA61K35/78) Mompon Bernard.
  16. 영남대학교 새마을지 역개발연구 v.17 쇠뜨기 성분의 항돌연변이원성에 관한 연구 정규찬;김미정
  17. Phytochem. Anal. v.11 Testing of antifungal natural products: methodologies, comparability of results and assay choice Hadacek, F.;Greger, H.
  18. Anal. Biochem. v.249 A microtiter -based fluorescence assay for (1,3)${\beta}$-glucan synthases Shedletzky, E.;Unger, C.;Delmer, D. P.
  19. Biol. Pharm. Bull v.19 Antioxidative effects of phenylethanoids from Cistanche deserticola Xiong, Q.;Kadota, S.;Tadata, T.;Namba, T.