Toxicological Research

  • 제20권4호
  • /
  • Pages.315-320
  • /
  • 2004
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  • 1976-8257(pISSN)
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  • 2234-2753(eISSN)
한국독성학회 (Korean Society of Toxicology & Korea Environmental Mutagen Society)
권호 표지

자외선 B 조사에 의한 마우스 피부 ATPase 양성 가지세포의 변화 및 녹차투여의 효과

The Change of ATPase-positive Dendritic Cell and the Effect of Green Tea in Mouse Skin by Ultraviolet B Irradiation

  • 김성호 (전남대학교 수의과대학) ;
  • 김세라 (전남대학교 수의과대학) ;
  • 이해준 (전남대학교 수의과대학) ;
  • 이진희 (전남대학교 수의과대학) ;
  • 김유진 (전남대학교 수의과대학) ;
  • 김종춘 (전남대학교 수의과대학) ;
  • 장종식 (상주대학교 축산학과) ;
  • 조성기 (한국원자력연구소 방사선이용연구부)
  • 발행 : 2004.09.01
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초록

In this study we assessed the influences of ultraviolet (UV) light B radiation on epidermal ATPase-positive dendritic cell (DC) and the effect of green tea treatment in ICR mouse. The extent of changes following 200 mJ/$cm^2$ (0.5 mW/sec) was studied at 0, 6, 12, 18, 24, 30 or 36 hours after exposure. SBCs were decreased by 6 hours after irradiation. There was tendency to decrease from 6 hours to 24 hours and had little further change from then to 36 hours after irradiation. The mice that received 0, 50, 100, 200, 300 or 400 mJ/$cm^2$ of UVB were examined 24 hours after irradiation. The DCs were decreased as the radiation dose increases from 100 to 400 mJ/$cm^2$. The frequency of UVB (200 mJ/$cm^2$)-induced DC decrease was reduced by treatment of green tea (i.p. and topical application, p<0.01).

키워드

참고문헌

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