Nutritional Sciences
- Volume 7 Issue 4
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- Pages.189-195
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- 2004
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- 1229-232X(pISSN)
Effects of Calorie Restriction on Microsomal Mixed Function Oxidase System and Free Radical in Kidney of SAMP8 Mice
- kim, Hyun-Jeong (Department of Food Science and Nutrition, Daegu Catholic University) ;
- Choi, Jin-Ho (Laboratory of Biochemistry, Pukyong National University) ;
- Rhee, Soon-Jae (Laboratory of Biochemistry, Pukyong National University)
- Published : 2004.11.01
Abstract
1bis study investigated the antioxidative effect in kidney of senescence-accelerated prone SAMP8 mice with calorie restriction. 4-weeks-old SAMP8 female mice were divided into 4 groups according to the experimental feeding period: for 4, 8, 12 month, and at natural death. Each group was subdivided into 2 groups, with thirteen mice each one, as ad libitum group and as dietary restriction group (60% of ad libitum feeding amount). After feeding for a given period, the mice were sacrificed to get the following results: among the experimental groups, there wereno significant differences in xanthine oxidase (XOD) activity in their kidney tissues. The contents of cytochrome