The Journal of Korean Medicine (대한한의학회지)

The Society of Korean Medicine (대한한의학회)
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Study on Relationship between Abdominal Connective Tissue Weakness and Interleukin-1 Gene Polymorphism in Iris Constitution Analysis Study on Relationship between Abdominal Connective Tissue Weakness and Interleukin-1 Gene Polymorphism in Iris Constitution Analysis

홍채 체질 분석에서 복부 결합조직 허약 체질과 인터루킨-1 유전자 다형성과의 상관성 연구

  • 도금록 (원광대학교 한의학 전문대학원 정보학과) ;
  • 황우준 (원광대학교 한의학 전문대학원 정보학과) ;
  • 금경수 (원광대학교 한의학 전문대학원 정보학과) ;
  • 최성용 (원광대학교 대학원 한의학과) ;
  • 김종욱 (원광대학교 대학원 한의학과) ;
  • 조재운 (원광대학교 대학원 한의학과)
  • Published : 2004.03.01
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Abstract

Objectives : The purpose of this study is to report the relationship between iridological constitution and interleukin 1 beta (IL-1 $\beta$) gene polymorphism. Methods : Iris constitution were diagnosed by automatic Iris analysis system, Bexel Irina(Korea). The blood was stored at - $20^{\circ}$... until it was ready to be extracted. The genomic DNA was extracted by inorganic procedure. The concentration of DNA was estimated by absorbance at 260 nm. The interleukin-1 beta (IL-1 $\beta$) gene polymorphism was detected by PCR amplification. Results & Conclusions : The author classified 166 individuals according to Iris constitution, and determined IL-1 $\beta$ genotype. The frequencies of Iris constitutions as follows : neurogenic type, 41 (24.7%); abdominal connective tissue weakness type, 53(31.9%); cardio-renal connective tissue weakness type, 50 (30.1%); the others type, 22 (13.3%). Especially, the frequency of abdominal connective tissue weakness type was significantly higher in err genotype than in the remaining constitutions. As a result, The author demonstrated the association among IL-1 $\beta$ genotype, IBD and Iris constitution.

Keywords

References

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