Archives of Pharmacal Research

  • 제27권6호
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  • Pages.589-593
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  • 2004
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  • 0253-6269(pISSN)
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  • 1976-3786(eISSN)
대한약학회 (The Pharmaceutical Society of Korea)
권호 표지

Flavonoids from Spatholobus Suberectus

  • Yoon, Jeong-Seon (College of Pharmacy and Research Institute of Pharmaceutical Science, Seoul National University) ;
  • Sung, Sang-Hyun (Institute for Life Science, Elcom Science Co. Ltd.) ;
  • Park, Jong-Hee (College of Pharmacy, Pusan National University) ;
  • Kim, Young-Choong (College of Pharmacy and Research Institute of Pharmaceutical Science, Seoul National University)
  • 발행 : 2004.06.01
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초록

Two pterocarpans ［(6aR,11aR）-maackiain, (6aR,11aR）-medicarpin］, one flavanone ［(2S）-7-hydroxy-G-methoxy-flavanone］, one isoflavan (sativan） and two isoflavones (pseudobaptigenin, genistein） were isolated from the Spatholobus suberectus (Leguminosae）. Their chemical structures were determined by comparison of their spectroscopic parameters of CD, ElMS, 1D-NMR and 2D-NMR with those reported in the literatures. All of these compounds are reported for the first time from this plant through the present study.

키워드

참고문헌

  1. Bonde, M, R., Millar, R. L., and Ingham., Induction and identification of sativan and vestitol as two phytoalexins from Lotus corniculatus. Phytochemistry, 12, 2957-2959 (1973) https://doi.org/10.1016/0031-9422(73)80514-X
  2. Cui Y. J., Liu P., and Chen R. Y., Studies on the chemical constituents of Spatholobus suberectus Dunn. Acta Pharmaceutica Sinia, 37, 784-787 (2002)
  3. Garcez, F. R., Scramin, S., Nascimento, M. C. D., and Mors, W. B., Prenylated flavonoids as evolutionary indicators in the genus Dahlstedtia, Phytochemistry, 27, 1079-1083 (1988) https://doi.org/10.1016/0031-9422(88)80277-2
  4. Harborne, J. B., The flavonoids : advances in research. Chapman & Hall, London, pp. 137-147, (1994)
  5. Herath, H. M. T. B., Dassanayake, R. S., Priyadarshani, A. M. A., Silva, S. D., Wannigama, G. P., and Jamie, J., Isoflavonoids and a pterocarpan from Gliricidia spedium. Phytochemistry, 47, 117-119 (1998) https://doi.org/10.1016/S0031-9422(97)00517-7
  6. Ingham, J. L., Isoflavonoid phytoalexins from leaves of Trifolium arvense. Z. Naturforsch., 320, 446-448 (1977)
  7. Ingham, J. L., Isolation and identification of Cicer isoflavonoids. Biochem. Syst. Ecol., 9, 125-128 (1981) https://doi.org/10.1016/0305-1978(81)90030-2
  8. Ingham, J. L., Phytoalexin production by Ononis species. Biochemcal Systematics and Ecology, 10, 233-237 (1982) https://doi.org/10.1016/0305-1978(82)90035-7
  9. Kim, J. G., and Cho, B. G., Traditional Drugs of The East. Young Lim Sa, Seoul, pp. 150-151, (1995)
  10. Kinjo, J. E., Furusawa, J. I., Baba, J., Takwshita, T., Yasaki, Y., and Nohara, T., Studiels on the constituents of Pueraria lobata. III. Isoflavonoids and related compounds in the roots and the voluble stems. Chem. Pharm. Bull., 35, 4846-4850 (1987) https://doi.org/10.1248/cpb.35.4846
  11. Kinoshita, T., Ichinose, K., Takahsh,i C., Ho, FC., Wu, JB., and Sakawa, U., Chemical studies on Sophora tomentosa: the isolation of a new class of isoflavonoid. Chem. Pharm. Bull., 38, 2756-2759 (1990) https://doi.org/10.1248/cpb.38.2756
  12. Lin, M., Li, S., Ebizuka, Y., and Mikawa, U., Chemical constituents of stem of suberect spatholobus (Spatholobus suberectus). Zhongcaoyao, 20, 53-56 (1989)
  13. Matsuda, H., Morikawa, T , Toguchida, I., Harima, S. and Yoshikawa, M., Medicinal flowers. VI. Absolute stereostructures of two new flavanone glycosides and a phenylbutanoid glycoside from the flowers of Chrysanthemum indicum L.: their inhibitory activities for rat lens aldose reductase, Chem. Pharm. Bull., 50, 972-975 (2002) https://doi.org/10.1248/cpb.50.972
  14. Maxzimo, P. and Lourenco, A., A pterocarpan from Ulex parviflorus, Phytochemistry, 48, 359-362 (1998) https://doi.org/10.1016/S0031-9422(97)01090-X
  15. Ohashi, H., Goto, M., and Imamura, H., Flavonoids from the wood of Cladrastis platycarpa. Phytochemistry, 15, 354-355 (1976) https://doi.org/10.1016/S0031-9422(00)89040-8
  16. Reddy, M. V. B., Reddy, M. K., Guvvuru, G., Caux, C., and Bodo, B., A flavanone and a dihydrodibenzoxepin from Bauhinia variegata, Phytochemistry, 64, 879-882 (2003) https://doi.org/10.1016/S0031-9422(03)00416-3
  17. Subarnas, A., Oshima, Y., and Hikino, H., Isoflavans and pterocarpan from Astragalus mongholicus. Phytochemistry, 30, 2777-2780 (1991) https://doi.org/10.1016/0031-9422(91)85143-N
  18. Tokes, A. L., Litkei, G., Gulacsi, K., Antus, S., Baitz-Gacs, E., Szantay., and Darko, L. L., Absolute configuration and total synthesis of (-)-cabenegrin A-I. Tetrahedron, 55, 9283-9296 (1999) https://doi.org/10.1016/S0040-4020(99)00490-1
  19. Zhu,Y. P., Chinese Materia Medica : Chemistry, pharmacology and applications. Harwood academic publishers, Netherland, pp. 468-470, (1988)