YAKHAK HOEJI (약학회지)

The Pharmaceutical Society of Korea (대한약학회)
권호 표지

Design and Synthesis of Anticonvulsive Agents as Potential Dual Acting Prodrugs and Their Anticonvulsive Activities

Dual Action 기능을 가지도록 설계한 항경련성 전구약물의 합성과 항경련 활성

  • Published : 2004.06.01
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Abstract

This study aimed to synthesize new anticonvulsive agents as potential dual acting prodrugs. For the synthesis of ester or amide prodrug types, p-hydroxybenzaldehyde or valproic acid was coupled with clinically usable anticonvulsants or GABAmimetics with use of DCC/DMAP coupling methods. Also their anticonvulsive activities were evaluated.

Keywords

References

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