Korean Mistletoe, Viscum album coloratum Induces Non-Specific Immune Responses in Japanese Flounder, Paralichthys olivaceus

  • Choi, Sang-Hoon (Department of Aquaculture life medicine, Kunsan National University) ;
  • Kim, Jong-Bae (Institute for Biomedical Research, Han Dong University) ;
  • Yoo, Yung-Choon (Department of Microbiology, College of Medicine, Konyang University) ;
  • Yoon, Taek-Joon (Department of Food Science and Biotechnology, Kyonggi University)
  • Published : 2004.08.01

Abstract

Effects of Korean mistletoe, Viscum album coloratum on the non-specific immune responses of Japanese flounder, Paralichthys olivaceus were examined. Flounder were inoculated with mistletoe, Freunds complete adjuvant (FCA), or phosphate-buffered saline (PBS) as a control into their peritoneal cavities. Reactive oxygen intermediate (ROI) products were more enhanced in mistletoe-injected fish kidney phagocytes than in FCA-injected ones. The level of lysozyme activity detected in the serum of fish 4 d after injection with mistletoe was also significantly higher than that found in the serum of the control fish. The appropriate concentration of mistletoe in eliciting the highest level of serum lysozyme activity was 500 $\mu$m/300 g of fish. In phagocytic activity assays, mistletoe-sen-sitized flounder kidney phagocytes captured more yeasts than those of the control fish. Korean mistletoe appeared to be a good activator of the non-specific immune responses of Japanese flounder.

Keywords

References

  1. Vet. Immunol. Immunopathol. v.34 Immunostimulants added to injected Aeromonas salmonicida bacterin enhance the defense mechanisms and protection in rainbow trout (Oncorhynchus mykiss) Anderson, D. P.;G. Jeney https://doi.org/10.1016/0165-2427(92)90177-R
  2. Pathol. Microbiol. v.38 Nonlinear response of the reticuloendothelial system upon stimulation Bliznakov, E. G.;A. D. Adler
  3. J. Exp. Biol. v.206 A role for nitric oxide in hypoxia-induced activation of cardiac KATP channels in goldfish (Carassius auratus) Cameron, J. S.;K. E. Hoffmann;C. Zia;H. M. Hemmett;A. Kronsteiner;C. M. Lee https://doi.org/10.1242/jeb.00655
  4. Inter. Immunophar. v.1 Cellular and humoral adjuvant activity of lectins isolated from Korean mistletoe (Viscum album colaratum) Taek, J. Y.;Y. C. Yoo;T. B. Kang;E. Her;S. H. Kim;K. Kim;I. Azuma;J. B. Kim https://doi.org/10.1016/S1567-5769(01)00024-8
  5. Bull. Soc. Chim. Biol. v.51 Differences in the behavior of chicken and goose egg white lysozymes against Micrococcus lysodeikticus Dianoux, A. C.;P. Jolles
  6. Science v.48 George Sarton and the history of medicine Fulton, J. F.
  7. Fish & Shellfish Immunol. v.9 Immunity to bacteria in fish Ellis, A. E. https://doi.org/10.1006/fsim.1998.0192
  8. Int. Arch. Allergy Appl. Immunol. v.76 no.Supp.1 Bacterial products as immunomodulating agents Gialdroni-Grassi, G.;C. Grassi https://doi.org/10.1159/000233742
  9. Oncology v.43 no.suppl.1 Immunomodulatory effect of Iscador: a Viscum album preparation Hajto, T. https://doi.org/10.1159/000226420
  10. Immunol. Today. v.15 Collectins: collagenous C-type lectins of the innate immune defense system Holmskov, U.;R. Malhotra;R. B. Sim;J. C. Jensenius https://doi.org/10.1016/0167-5699(94)90136-8
  11. J. Fish Dis. v.27 Detection and antigenic characterization of salmonid alphavirus isolates from sera obtained from farmed Atlantic salmon, Salmo salar L., and farmed rainbow trout, Oncorhynchus mykiss (Walbaum) Jewhurst, V. A.;D. Todd;H. M. Rowley;I. W. Walker;J. H. Weston;M. F., McLoughlin;D. A. Graham https://doi.org/10.1111/j.1365-2761.2004.00530.x
  12. Fish & Shellfish Immunol. v.11 Immunostimulatory CpG oligodeoxynucleotides stimulate expression of IL-1beta and interferon-like cytokines in rainbow trout macrophages via a chloroquine-sensitive mechanism Jorgensen, J. B.;J. Zou;A. Johansen;C. J. Secombes https://doi.org/10.1006/fsim.2001.0344
  13. Gen. Comp. Endocrinol. v.58 Control of renal and adrenocortical function by the renin-angiotensin system in two euryhaline teleost fishes Kenyon, C. J.;A. McKeever;J. A. Oliver;I. W. Henderson https://doi.org/10.1016/0016-6480(85)90140-6
  14. J. Exp. Clin. Cancer Res. v.11 Tumor reducing activity of an isolated active ingredient from mistletoe extract and its possible mechanism of action Kuttan, G.;D. M. Vasudevan;R. Kuttan
  15. Bioessays v.19 Collectins: collectors of microorganisms for the innate immune system Lu, J. https://doi.org/10.1002/bies.950190610
  16. Arch. Pharm. Res. v.23 Comparative study of Korean (Viscum album var. coloratum) and European mistletoe (Viscum album) Lyu, S. Y.;S. M. Park;B. Y. Choung;:W. B. Park https://doi.org/10.1007/BF02975247
  17. Cance Immunol. Immunother. v.33 Induction of tumor necrosis factor expression by a lectin from Viscum album Mannel, D. N.;H. Becker;A. Gundt;H. Franz https://doi.org/10.1007/BF01756139
  18. Aquaculture v.101 Protective effect of schizophyllan and scleroglucan against Streptococcus sp. Infection in yellowtail (Seriola quinqueradiata) Matsuyama, H.;R. E. P. Mangindaan;T. Yano https://doi.org/10.1016/0044-8486(92)90023-E
  19. Immunobiol. v.169 The in vitro activity of lectin 1 from mistletoe (ML 1) and its isolated A and B chains in fuctions of macrophages and polymorphonuclear cells Mertzer, G.;H. Franz;A. Kindt;B. Fahlbusch;J. Sus https://doi.org/10.1016/S0171-2985(85)80002-4
  20. Fish & Shellfish Immunol. v.8 Fuctional characterisation of a macrophage-activating factor produced by leucocytes of gilthead seabream (Sparus aurata L.) Mulero, V.;J. Meseguer https://doi.org/10.1006/fsim.1997.0127
  21. Canaer Immunol. Immunother. v.32 Viscum album oligosacchaaride activating human natural cytotoxicity is an interferon gamma inducer Mueller, E. A.;F. A. Anderer https://doi.org/10.1007/BF01741704
  22. Vet. Immunol. Immunopathol. v.55 Lectin-carbohydrate interaction in the immune system Ni, Y.;I. Tizard https://doi.org/10.1016/S0165-2427(96)05718-2
  23. Immunogenetics v.38 Cloning of the beta 2-microglobulin gene in the zebrafish Ono, H.;F. Figueroa;C. O'hUigin;J. Klein https://doi.org/10.1007/BF00216384
  24. J. Fish Dis. v.24 Immunostimulant effects of nucleotide isolated from yeast RNA on carp, Cyprinus carpio L. Sakai, M.;K. Taniguchi;K. Mamoto;H. Ogawa;M. Tabata https://doi.org/10.1046/j.1365-2761.2001.00314.x
  25. Fish & shellfish Immunol. v.7 Effect of betaglucans on the non-specific immune response of turbot (Scophthalmus L.) Santarem, M.;B. Novoa;A. Figueras https://doi.org/10.1006/fsim.1997.0096
  26. Dev. Comp. Immunol. v.12 Superoxide anion production by rainbow trout macrophages detected by the reduction of ferricytochrome C. Secombes, C. J.;S. Chung;A. H. Jeffries https://doi.org/10.1016/0145-305X(88)90038-9
  27. Dev. Comp. Immunol. v.26 Channel catfish cytotoxic cells: a mini-review Shen, L.;T. B. Stuge;H. Zhou;M. Khayat;K. S. Barker;S. M. Quiniou;M. Wilson;E. Bengten;V. G. Chinchar;L. W. Clem;N. W. Miller https://doi.org/10.1016/S0145-305X(01)00056-8
  28. Brain Res. v.11 Neuronal nitric oxide synthase in the olfactory system of an adult teleost fish Oreochromis mossambicus Singru, P. S.;A. J. Sakharkar;N. Subhedar
  29. Ecotoxicol. Environ. Saf. v.19 In vivo effect of the organophosphorus insecticide trichlorphon on immune response of carp (Cyprinus carpio). II. Effect of high doses of trichlorphon on nonspecific immune response Siwicki, A. K.;M. Cossarini-Dunier;M. Studnicka;A. Demael https://doi.org/10.1016/0147-6513(90)90084-I
  30. Fish & Shellfish Immunol. v.11 Respiratory burst of turbot (Scophthalmus maximus) macrophages in response to experimental infection with viral haemorrhagic septicaemia virus(VHSV) Tafalla, C.;B. Novoa https://doi.org/10.1006/fsim.2001.0346
  31. Ann. N. Y. Acad. Sci. v.15 Animal lectins as self/nonself recognition molecules. Biochemical and genetic approaches to understanding their biological roles and evolution Vasta, G. R.;H. Ahmed;N. E. Fink;M. T. Elola;A. G. A. M. Snowden; E. W. Odom
  32. Immunol. Rev. v.163 The C-type lectin superfamily in the immune system Weis, W. I.;M. E. Taylor;K. Drickamer https://doi.org/10.1111/j.1600-065X.1998.tb01185.x
  33. Int. Immunopharmacol. v.1 Cellular and humoral adjuvant activity of lectins isolated from Korean mistletoe (Viscum album colaratum) Yoon, T. J.;Y. C. Yoo;T. B. Kang;E. Her;K. Kim;I. Azuma;J. B. Kim https://doi.org/10.1016/S1567-5769(01)00024-8