The Effect of Highly Concentrated Oxygen Administration on Cerebrum Lateralization of Young Men during Visuospatial Task

고농도의 산소 공급이 공간지각 과제 수행 시 젊은 성인 남자의 대뇌 편측화에 미치는 영향

  • Published : 2004.08.01

Abstract

The present study attempted to investigate the effects of supply of highly concentrated (30%) oxygen on human ability of visuospatial cognition and cerebrum lateralization. compared to air of normal oxygen concentration (21%). The experiment consisted of two runs, one fur visuospatial cognition test with normal air (21% of oxygen) and for visuospatial cognition test with more oxygen in the air (30% of oxygen). Each run was composed of four blocks and each block included eight control tasks and five visuospatial tasks. Functional brain images were taken from 3T MRI using the single-shot EPI method. The result of task performance showed the accuracy increased at 30%'s concentration of oxygen rather than 21%'s. There were more activations observed at the left and right hemisphere, but there was decrease cerebrum lateralization with 30% oxygen administration. Thus, it is concluded that the positive effect on the visuospatial cognitive performance level by the highly concentrated oxygen administration was due to increase of cerebrum activation and decrease of cerebrum lateralization

Keywords

References

  1. Horwitz, B., McIntosh, A.R., Haxby, J.V., Grady, C.L., 'Network analysis of brain cognitive function using metabolic and blood-flow data,' Behav. Brain Res, Vol. 66, pp. 187-193, 1995 https://doi.org/10.1016/0166-4328(94)00139-7
  2. Crowley, J.S., Wesenten, N.W., Kamimori, G., Devine, M.E., Iwanyk, E., Balkin, T., 'Effects of high terrestrial altitude and supplemental oxygen on human performance and mood,' Aviat. Space Environ. Med, Vol. 63, pp. 696-701, 1992
  3. Eustache, F., Rioux, P., Desgranges, B., Marchal, G., Petittaboue, M.C., Dary, M., Lechevalier, B., Baron, J.C., 'Healthy aging, memory subsystems and regional cerebral oxygen consumption,' Neuropsychologia, Vol. 33, pp. 867-887, 1995 https://doi.org/10.1016/0028-3932(95)00021-T
  4. Moss, M.C., Scholey, A.B., 'Oxygen administraion enhances memory formation in healthy young adults,' Psychopharmacology, Vol. 124, pp. 255-260, 1996 https://doi.org/10.1007/BF02246665
  5. Scholey, A.B., Moss, M.C., Neave, N., lWesnes, K., 'Cognitive performance, hyperoxia, and heart rate following oxygen administration in healthy young adults,' Physiology & Behavior, Vol. 67, No. 5, pp. 783-789, 1999 https://doi.org/10.1016/S0031-9384(99)00183-3
  6. Chung, S.C., Kim, I.H., Lee, B., Lee, J.M, ;Sohn, J.H., Kim, S.C., 'A Study on visuospatial cognitive performance following oxygen administration using fMRI,' J. of the KSMBE, Vol. 24, No. 4, pp. 267-273, 2003
  7. Springer, S.P., Deutsch, G., 'Left Brain, Right Brain,' 5th edn., W.H. Freeman, New York, 1988
  8. Fink, G.R., Marshall, J.C., Weiss, P.H., Zilles, K., 'The neural basis of vertical and horizontal line bisection judgements: an fMRI study of normal volunteers,' Neuroimage, Vol. 14, No. 1, pp. 59-67, 2001 https://doi.org/10.1006/nimg.2001.0819
  9. Ng, V.W., Eslinger, P.J., Williams, S.C., Brammer, M.J., Bullmore, E.T., Andrew, C.M., Suckling, J., Morris, R.G., Benton, A.L., 'Hemispheric preference in visuospatial processing: a complementary approach with fMRI and lesion studies,' Human Brain Mapping, Vol. 10, No. 2, pp. 80-86, 2000 https://doi.org/10.1002/(SICI)1097-0193(200006)10:2<80::AID-HBM40>3.0.CO;2-2
  10. Ng, V.W., Bullmore, E.T., de Zubicaray, G.I., Cooper, A., Suckling, J., Williams, S.C., 'Identifying rate-limiting nodes in large-scale cortical networks for visuospatial processing: an illustration using fMRI,' Journal of Cognitive Neuroscience, Vol. 13, No. 4, pp. 538-545, 2001 https://doi.org/10.1162/08989290152001943
  11. Gur, R.C., Alsop, D., Glahn, D., Petty, R., Swanson, C.L., Maldjian, J.A., Turetsky, B. I., Detre, J.A., Gee, J., Gur, R.E., 'An fMRI study of sex differences in regional activation to a verbal and a spatial task,' Brain and Language, Vol. 74, pp. 157-170, 2000 https://doi.org/10.1006/brln.2000.2325
  12. Sohn, J.H., Kim, Y.H., Lee, K.H., Park, S.H., 'Brain areas activated by different levels of individual's visuospatial ability: an fMRI study,' Korean Journal of Brain Science and Technology, Vol. 1, No. 2, pp. 201-209, 2001
  13. Vitouch, O., Bauer, H., Gittler, G., Leodolter, M., Leodolter, U., 'Cortical activity of good and poor spatial test performances during and spatial and verbal processing studied with slow potential topography,' International Journal of Psychology, Vol. 27, pp. 183-199, 1997 https://doi.org/10.1016/S0167-8760(97)00060-3
  14. Lee, S.R., 'Intelligence test 151-Ga Type (High school students ${\sim}$ adults),' Jungangjucksung Press, Seoul, Korea, 1982
  15. Lee, S.R., Kim, K.R., 'Aptitude test 251-Ga (High school students ${\sim}$ adults),' Jungangjucksung Press, Seoul, Korea, 1985
  16. Park, S.B., 'GATB (General Aptitude Test Battery): academic, job aptitude test type Ⅱ (for students of middle schools, high schools and universities, and general public),' Jungangjucksung Press, Seoul, Korea, 1985
  17. Talairach, J., Tournoux, P., 'Co-Planar Stereotaxic Atlas of the Human Brain,' Georg Thieme Verlag, Stuttgart, New York, 1988