Food Science of Animal Resources (한국축산식품학회지)

Korean Society for Food Science of Animal Resources (한국축산식품학회)
권호 표지

The Effect of Hangover Drink using Propolis on Ethanol Oxidation

프로폴리스를 이용한 숙취 해소 음료의 알콜 분해 효과

  • Published : 2004.06.01
Download PDF
⟨ Previous Next ⟩

Abstract

The studies was conducted to investigate the effect of hangover drink using natural products propolis on ethanol oxidation. The hangover drink developed using propolis concentrates and various medicinal plants. The extractions of propolis and acanthopanax senticosus was shown the highest alcohol oxidation among the combination raw. The ethanol oxidation effect were not significantly different between propolis drink and in other company products in acute alcoholic toxic doses. In the case that it was conducted oral administration with acute alcoholic toxic doses 1/3(1.8mg per 1kg body weight of mouse), propolis drink comparative products of other company was shown 0.026％ to 270 min, 0.000％ to 360 min. In conclusion, propolis drink was shown excellent alcohol oxidation in fixed dose of alcohol, but was not shown in a large quantities of alcohol.

천연발효물질인 프로폴리스를 이용하여 숙취 해소 음료를 개발하고 그에 따른 알콜 대사에 미치는 효과를 알아보고자 하였다. 프로폴리스 농축액과 다양한 약용식물의 농축액을 사용하여 숙취 해소 음료를 개발하였다. 배합원료 각각의 알콜 분해 능력을 검토한 결과, 프로폴리스와 가시오가피 추출액이 가장 큰 분해 능력을 보였다. 타 회사 제품과의 알콜 분해 능력을 비교한 경우 급성 주정 중독량 (kg당 4g)을 경구 투여하였을 때 유의적인 차이를 보이지 않았다. 그러나 주정중독량 지표보다 약 1/3을 감소시킨 kg당 1.8 L의 술을 경구 투여한 경우, 프로폴리스 음료는 270분이 경과했을 때 0.026%, 360분이 경과했을 때에는 0.000%의 혈중알콜농도를 나타내었다. 이것으로 보아 프로폴리스 음료는 섭취알콜의 양이 많을 경우에는 큰 차이가 없었지만, 일정량의 알콜을 섭취할 경우에는 매우 뛰어난 알콜 분해 효능이 있음을 알 수 있었다.

Keywords

References

  1. Bevilacqua, M., Bevilacqua, M., Serra, E., Vianello, A., Garrou, E., Sparagna, B., Barale, U., and Zaccagna, C. A. (1997) Natural resin association such as incense and propolis in zootechnology. Agric. Eco. Environ. 62, 247-252 https://doi.org/10.1016/S0167-8809(96)01131-0
  2. Chiao, C., Carothers, A. M., Grunberger, D., Solomon, G., Preston, A., and Barrett, J. C. (1995) Apoptosis and altered redox state induced by caffeic acid phenethylester in transformed rat fibroblast cells. Cancer Res. 55, 3576-3579
  3. Cuellar, C. A., Rojas Hernandez, N. M., and Martinez Perez, J. (1990) New antimicrobial structure from propolis collected in Cuba. Revta-Cubana-de-Farmacia. 24, 51-54
  4. Erben-Russ, M., Bors, W., and Saran, M. (1987) Reactions of linoleic and peroxyl radicals with phenolic antioxidants pulse radiolysis study. Int. J. Radiat. BioI. 52, 393-397 https://doi.org/10.1080/09553008714551871
  5. Ikeno, K., Ikeno, T., and Miyazawa, T. (1994) Effects of propolis on dental caries in rats. Honeybee Sci. 15: 1-6
  6. Kweon, M. H., Hwang, H. J., and Sung, H. C. (2001) Identification and antioxidant activity of novel chioro-genic acid derivatives from bamboo (Phyllostachys edulis). J. Agric. Food Chem. 49, 4646-4655 https://doi.org/10.1021/jf010514x
  7. Marshall, E. K. and Fritz, W. F. (1953) The metabolism of ethyl alcohol. J. Pharmacol. Exp. Ther. 109, 431-445
  8. Mathmoto, C. (1994) Miracle Maesil Method, Kookilmunhwasa, Korea (in Korean)
  9. Matsuno, T. (1992) Isolation and characterization of the tumoricidal substances from brazilian propolis. Honeybee Sci. 13, 49-53
  10. Rojas hernandez, N. M. and de la, K. Cuetara Bernal. (1990) Antibiotic effect of propolis against strains of Staphylococcus aureus of human clinical origin. Revta-Cubana- de-Farmacia. 24, 45-48
  11. Siess, M. H., Lebon, A. M., Canivenclavier, M. C., Amiot, M. J., Sabatier, S., Aubert, S. Y., and Suschetet, M. (1996) Flavonoids of honey and propolis-characteri-zation and effects on hepatic drug-metabolizing enzymesnd benzo(A) pyrene-DNA binding in rats. J. Agric. Food Chem. 44, 2297-2301 https://doi.org/10.1021/jf9504733
  12. Swift, R. and Davidson, D. (1998) Alcohol hangover, mechanisms and mediators. Alcohol Health Res. World 22, 54-60
  13. Takahama, U., Youngman, R. J., and Elstner, E. F. (1984) Transformation of quercetin by singlet oxygen generated by photosensitized reaction. Photobiochem. and Photobiophysics. 7, 175-179
  14. Takaisi-kikuni, N. B. and Schilcher, H. (1994) Electron microscopic and microcalorimetric investigations of the possible mechanism of the antibacterial action of a defined-propolis provenance. Planta Medica. 60, 222-226 https://doi.org/10.1055/s-2006-959463
  15. Takino, Y. and Mochida, S. (1982) Propolis, its chemical constituents and biological activities. Honeybee Sci. 3, 145-149
  16. 김정상(2004) 갈근과 죽력을 함유한 숙취해소 음료가 알코올 투여한 생쥐에 미치는 영향. 한국식품영양과학회지. 33(2), 318-323