Biomedical Science Letters (대한의생명과학회지)
- Volume 10 Issue 2
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- Pages.143-151
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- 2004
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- 1738-3226(pISSN)
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- 2288-7415(eISSN)
Platelet-Activating Factor Enhances Experimental Pulmonary Metastasis of Murine Sarcoma Cells by Up-regulation of Matrix Metalloproteinases-9 Through NF-$\kappa$ B-Dependent Pathway
- Ko, Hyun-Mi (Basic Sciences Research Institute, Chonnan National University) ;
- Back, Hae-Kyong (Clinical Laboratory, Kwangju Christian Hospital)
- Published : 2004.06.01
Abstract
Matrix metalloproteinases (MMPs) are capable of degrading extracellular matrix, a process that is necessary for angiogenesis, tumor invasion and metastasis. Platelet-activating factor (PAP) increases angiogenesis, tumor growth and metastasis through nuclear factor (NF)-
Keywords
- Matrix metalloproteinases (MMPs);
- Platelet-activating factor (PAF);
- Nuclear factor (NF)-kB;
- Metastasis