Parasites, Hosts and Diseases

The Korea Society for Parasitology and Tropical Medicine (대한기생충학·열대의학회)
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Susceptibility of several strains of mice to Echinostoma hortense infection

  • Lee, Kyu-Jae (Department of Parasitology and Institute of Basic Medical Science) ;
  • Park, Seung-Kyu (Department of Parasitology and Institute of Basic Medical Science) ;
  • Im, Jee-Aee (Department of Biomedical Laboratory Science and Institute of Health Science, College of Health Science, Yonsei University) ;
  • Kim, Soo-Kie (Department of Microbiology Wonju College of Medicine, Yonsei University) ;
  • Kim, Geun-Ha (Department of Biomedical Laboratory Science and Institute of Health Science, College of Health Science, Yonsei University) ;
  • Kim, Gwang-Young (Department of Biomedical Laboratory Science and Institute of Health Science, College of Health Science, Yonsei University) ;
  • Yang, Eun-Ju (Department of Biomedical Laboratory Science and Institute of Health Science, College of Health Science, Yonsei University) ;
  • Ryang, Yong-Suk (Department of Biomedical Laboratory Science and Institute of Health Science, College of Health Science, Yonsei University)
  • Published : 2004.06.01
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Abstract

Susceptibilities of 5 different mice strains, including C3H/HeN, BALB/c, C57BL6, FvB and ICR, to Echinostoma hortense infection, was evaluated. The worm expulsion rate, worm size and egg production were observed from 1 to 8 weeks after infection with 30 metacercariae. C3H/HeN and ICR mice showed the highest worm maturation rates. The worm recovery rate and the number of eggs per gram (EPG) of feces was also higher in C3H/HeN and ICR mice than in BALB/c, C57BL6, and FvB mice. It is suggested that E. hortense is highly infectious to ICR and C3H/HeN mice, but not to the other strains of mice. Based on the results obtained, we believe that the susceptibility of different mouse strains to E. hortense infection is dependent on the genetic and immunologic back-ground of mice.

Keywords

References

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