대한수의학회지 (Korean Journal of Veterinary Research)

  • 제44권4호
  • /
  • Pages.649-653
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  • 2004
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  • 2466-1384(pISSN)
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  • 2466-1392(eISSN)
대한수의학회 (The Korean Society of Veterinary Science)
권호 표지

Evaluation of clinical usefulness of reference interval of some selected hematological parameters in canine blood

  • Pak, Son-Il (Department of Veterinary Medicine, Kangwon National University) ;
  • Han, Ho-Jae (College of Veterinary Medicine, Chonnam National University)
  • 심사 : 2004.05.10
  • 발행 : 2004.12.30
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초록

To estimate the source of variance components for some hematological parameters and assess the utility of the conventional population-based reference interval, this study computed index of individuality for blood samples, which were from 13 dogs drawn once weekly for 4 consecutive weeks. Results were subjected to nested analysis of variance. For all parameters measured between-dog variations were greater than within-dog variation. Except for the parameters RBC and MCHC the index of individuality was <1.4. The low reliability coefficient and high index of individuality of ${\leq}0.8$ were found for the majority of hematological parameters. In practical term, the present study indicated that use of hemogram profiles alone in the evaluating clinical state of a single patient should be avoided because of their physiological or natural random variations, and that comparing a single measurement on the blood analytes from an individual dog to the conventional population-based reference range may be too insensitive to detect any significant changes in the blood components of that particular dog. A single measurement may not characterize an individual's average concentration of the parameters even shortterm period.

키워드

참고문헌

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