The Journal of Korean Physical Therapy
- 제16권2호
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- Pages.63-71
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- 2004
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- 1229-0475(pISSN)
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- 2287-156X(eISSN)
전기자극치료가 흰쥐 탈 신경근연접부에서 NT-3의 발현에 미치는 영향
The effects of Electrical Stimulation Therapy on NT-3 Expression in the Denervated Neuromuscular Junction in Rat
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남기원
(대구대학교 재활과학대학 물리치료학과 신경재생실)
;
- 구현모 (대구대학교 대학원 재활과학과 물리치료) ;
- 천송희 (대구대학교 대학원 재활과학과 물리치료) ;
- 이윤섭 (대구대학교 대학원 재활과학과 물리치료) ;
- 강종호 (대구대학교 재활과학대학원 재활과학과 물리치료) ;
-
김진상
(대구대학교 재활과학대학 물리치료학과)
-
Nam Ki-Won
(Nerve Regeneration Laboratory, Dept. of Physical Therapy, College of Rehabilitation Science, Daegu University)
;
- Koo Hyun-Mo (Major in Physical Therapy, Dept. of Rehabilitation Science, Graduate School, Daegu University) ;
- Cheon Song-Hee (Major in Physical Therapy, Dept. of Rehabilitation Science, Graduate School, Daegu University) ;
- Lee Yun-Seop (Major in Physical Therapy, Dept. of Rehabilitation Science, Graduate School, Daegu University) ;
- Kang Jong-Ho (Major in Physical Therapy, Dept. of Rehabilitation Science, Graduate School of Rehabilitation Science, Daegu University) ;
-
Kim Jin-Sang
(Dept. of Physical Therapy, College of Rehabilitation Science, Daegu University)
- 발행 : 2004.06.01
초록
Denervated skeletal muscle produces muscle atrophy as well as changes at the neuromuscular junction which leads to terminal axonal sprouting and an ultrastructural remodeling. NT-3 is expressed in adult muscle and motoneurons. Normally NT-3 has a potential role in regulating adult neuromuscular jungtion and recovering following muscle atrophy. Also, it could influence synaptic neurotransmission between motoneurons and skeletal muscle cells. The purpose of this study was to investigate the effect of electrical stimulation therapy(EST) on NT-3 expression in neuromuscular junction following sciatic nerve transsection in rats. After EST application during 7 days, the immunoreactivity of NT-3 was increased in neuromuscular junction
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