Journal of Gastric Cancer

The Korean Gastric Cancer Association (대한위암학회)
권호 표지

Prognostic Significance of Group 2 Lymph Node Metastasis in pT3pN1 Gastric Cancer Patients

제5판 UICC TNM림프절 분류에 따른 pT3pN1 위암 환자에서 림프절의 해부학적인 위치에 따른 2군 림프절 양성의 의의

  • Kim Yong Jin (Department of Surgery Gastrointestinal Division, University of Ulsan College of Medicine and Asan Medical Center) ;
  • Kim Byung Sik (Department of Surgery Gastrointestinal Division, University of Ulsan College of Medicine and Asan Medical Center) ;
  • Choi Won Yong (Department of Surgery Gastrointestinal Division, University of Ulsan College of Medicine and Asan Medical Center) ;
  • Yook Jung Hwan (Department of Surgery Gastrointestinal Division, University of Ulsan College of Medicine and Asan Medical Center) ;
  • Oh Sung Tae (Department of Surgery Gastrointestinal Division, University of Ulsan College of Medicine and Asan Medical Center) ;
  • Park Kun Choon (Department of Surgery Gastrointestinal Division, University of Ulsan College of Medicine and Asan Medical Center)
  • 김용진 (울산대학교 의과대학 서울아산병원 외과학교실) ;
  • 김병식 (울산대학교 의과대학 서울아산병원 외과학교실) ;
  • 최원용 (울산대학교 의과대학 서울아산병원 외과학교실) ;
  • 육정환 (울산대학교 의과대학 서울아산병원 외과학교실) ;
  • 오성태 (울산대학교 의과대학 서울아산병원 외과학교실) ;
  • 박건춘 (울산대학교 의과대학 서울아산병원 외과학교실)
  • Published : 2004.03.01
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Abstract

Purpose: The most important prognostic factors in gastric cancer is the depth of invasion of the primary tumor and lymph node metastasis. The nodal staging of the 5th edition of the Union Internationale Contrala Cancrums (UICC) TNM classification in 1997 was changed based on the number of metastatic lymph node. We attempted to evaluate the prognostic significance of N2 group metastasis in pT3pN1 gastric cancer patients by comparing two different nodal staging systems. Materials and Methods: A retrospective analysis was made for 352 gastric cancer patients who underwent curative resection, including D2 dissection, from 1991 to 1997 at Asan Medical Center. A clinicopathologic comparison between two groups by using a nodal staging systems was summarized into a table. Cumulative survival rates were calculated by using the Kaplan-Meier method. The difference between the two groups was evaluated by using the log rank test with SPSS 11.5 for Windows Results: There were no statistical differences in clinicopathologic factors. However, there was a significant difference in survival rate between the two groups (P=0.0009). This suggests that N2 group metastasis in pT3pN1 gastric cancer patients has a clinical significance for predicting prognosis. Conclusion: Our results suggest a possibility of prognostic significance of N2 group metastasis. Therefore, anatomical location of the lymph node should be described.

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