Journal of the Korean Association of Oral and Maxillofacial Surgeons

The Korean Association of Oral and Maxillofacial Surgeons (대한구강악안면외과학회)
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BIOLOGIGIC MEMBRANE FOR GUIDED BONE REGENERATION

골 재생을 위한 생물학적 유도막

  • Hong, Jong-Rak (Department of Oral & Maxillofacial Surgery, College of Dentistry, Seoul National University) ;
  • Kang, Na-Ra (Department of Oral & Maxillofacial Surgery, College of Dentistry, Seoul National University) ;
  • Choung, Pill-Hoon (Department of Oral & Maxillofacial Surgery, College of Dentistry, Seoul National University)
  • 홍종락 (서울대학교 치과대학 구강악안면외과학교실) ;
  • 강나라 (서울대학교 치과대학 구강악안면외과학교실) ;
  • 정필훈 (서울대학교 치과대학 구강악안면외과학교실)
  • Published : 2004.02.28
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Abstract

The purpose of this study was to evaluate the stability and efficacy of biologic membrane made of freeze-dried cartilage as a barrier to facilitate guided bone regeneration in experimental non-healing bone defects in the rat mandible. Nine adult Sprague-Dawley rats (400-500g) were used in experiment. 5.0mm in diameter were created on the mandibular angle area by means of slow-speed trephine drill. In microscopic examination, dynamic immature bone forming at 2 weeks and its calcification at 4 weeks were observed. The membrane made of lyophilized cartilage taken from human costal cartilage seems to be very effective for guided bone regeneration as a biologic membrane and the scaffold for attachment of cells or local drug delivery system of growth factor, which may meet the ideal requirement of a barrier membrane and graft materials.

Keywords

References

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