한국약용작물학회지 (Korean Journal of Medicinal Crop Science)

  • 제12권3호
  • /
  • Pages.191-202
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  • 2004
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  • 1225-9306(pISSN)
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  • 2288-0186(eISSN)
한국약용작물학회 (The Korean Society of Medicinal Crop Science)
권호 표지

한국산 약용식물로부터의 SOD활성 및 Phenolic Compounds 함량 비교

Comparision of SOD Activity and Phenolic Compound Contents in Various Korean Medicinal Plants

  • 임정대 (강원대학교 농생대 식물응용과학부) ;
  • 유창연 (강원대학교 농생대 식물응용과학부) ;
  • 김명조 (강원대학교 농생대 식물응용과학부) ;
  • 윤성중 (전북대학교 생물자원과학부) ;
  • 이선주 (건국대학교 생명환경과학대학) ;
  • 김나영 (경희대학교 식품영양학과) ;
  • 정일민 (건국대학교 생명환경과학대학)
  • Lim, Jung-Dae (College of Agriculture & Life Sci., Kangwon Natl. Univ.) ;
  • Yu, Chang-Yeon (College of Agriculture & Life Sci., Kangwon Natl. Univ.) ;
  • Kim, Myong-Jo (College of Agriculture & Life Sci., Kangwon Natl. Univ.) ;
  • Yun, Song-Joong (Division of Biological Resources Sci., Chonbuk Natl. Univ.) ;
  • Lee, Sun-Ju (College of Life and Environment Sci., Konkuk Univ.) ;
  • Kim, Na-Young (Department of Food & Nutrition, Kyung Hee Univ.) ;
  • Chung, Ill-Min (College of Life and Environment Sci., Konkuk Univ.)
  • 발행 : 2004.06.30
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초록

한국에 분포하고 있는 82종의 약용식물에 대하여 환경내성 및 기능성 소재의 개발을 위한 탐색을 위하여 항산화효소와 관련된 첫 번째 방어기작인 SOD 효소활성과 Phenol 화합물의 함량정도를 검정하여 본 결과 SOD 효소활성은 원지 (P. tenuifolia Willd.), 백편두 (D. lablab L.), 백개자 (S. alba L.), 대황 (R. palmatum L.), 감초 (G. uralensis Fisch), 연자육 (N. nucifera Gaertn), 지황 [R. glutinosa (Gaertner) Liboshitz], 현삼 (S. buergeriana Miq.), 인진 (A. capillaris Thb.)등에서 다른 약용작물보다 비교적 높은 SOD 효소 활성 능력을 나타냈다. Total phenol함량은 $(3{\sim}249.731\;{\mu}g/g)$의 범위를 보였으며 지유(S. officinalis L.), 대황 (R. palmatum L.), 복분자 (R. chingii Hu)에서 각각 $249.731\;{\mu}g/g,\;209.546\;{\mu}g/g,\;170.333\;{\mu}g/g$으로 가장 높은 함량을 나타냈다. 16종의 phenol 화합물의 경우에서는 82종의 약용식물이 각기 매우 상이한 농도의 분포를 나타내었다. 앞으로의 연구에서는, 항산화 효소 및 phenol 화합물이 많이 함유하여 우수한 기능성을 가지고 있는 것을 확인된 약용식물에 대해 그들의 이용성을 증대시킬 수 있는 구체적인 연구가 수행되어져야 할 것으로 사료된다. 또한 phenol성 물질을 많이 함유하는 약용식물 추출물을 이용한 기능성 식품, 화장품, 천연 보존재 및 의약품 등으로 개발 (Cook & Samman, 1996)할 수 있을 것으로 판단되어진다.

82 species of Korean medicinal plants were measured to their SOD (superoxide dismutase) activity, total phenol and individual phenol compounds. The SOD activity of medicinal plants was varied from 3.67% to 48.3%, and especially, 4 species including Polygala tenuifolia Willd. showed activity over 40% higher than other species. The 16 individual phenol compounds concentrations have a severe variation in medicinal plants. Codonopsis lanceolata is the highest concentration $(12,176\;{\mu}g/g)$, and 10 species including Glycyrrhiza uralensis Fisch were showed to concentrations more than $1,000\;{\mu}g/g$. And also, salicylic acid was generally found in many plants, but trans-cinnamic acid, naringenin and kampferol was little found in plants. The total phenol by Folin-Dennis methods showed a respectively variation $(3{\sim}249.731\;{\mu}g/g)$ in 82 medicinal plants, and 7 species including Astragalus membranaceus showed low total phenol concentrations less than $10\;{\mu}g/g$. In conclusion, we expect that selecting medicinal plants with high biological activity might develop to chemicals related to antioxidants, as well as these become most popular substance at many industrial materials, and suggest to more researchs in future.

키워드

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