백지의 콜라겐 생성 촉진 물질

Promoting Synthesis of Collagen from Angelica dahurica Root

  • 발행 : 2004.12.30

초록

Three coumarin derivatives, which stimulate collagen biosynthesis in human fibroblasts were isolated from Angelica dahurica root which has been used in traditional medicine for cold, headache, discharging blood and women's diseases. Three coumarin derivatives were identified as 5-benzofuranacrylic acid, $6,7-dihydroxy-4-(3-methyl-2-butenyl)-{\delta}-lactone\;(prangenidin)$, 5-benzofuranacrylic acid, $6,7-dihydroxy-4-methoxy-{\delta}-lactone\;(8-hydroxybergapten)$ and 5-benzofuranacrylic acid, 8-hydroxypsoralen(xanthotoxol) from their spectral data.

키워드

참고문헌

  1. Jerome S. P., Gabrielle L., and Raul F. (1998) Identification of Collagen Fibrils in scleroderma skin. J. Invest. Dermatol. 90(1): 48-54 https://doi.org/10.1111/1523-1747.ep12462561
  2. Balin K. and Kligman A. M. (1989) Aging and Skin, Raven press
  3. El-Domyati M., Attia S., Saleh F., Brown D., Birk D. E., Gasparro F., Ahmad H., and Uitto J. (2002) Intrinsic aging vs. photoaging : a comparative histopathological, immuno-histochemical, and ultrastructural study of skin. Exp. Dermatol. 11(5): 398-405 https://doi.org/10.1034/j.1600-0625.2002.110502.x
  4. Giacomoni, P. U. and Rein, G. (2001) Factors of skin ageing share common mechanisms. Biogerontology, 2(4): 219-229 https://doi.org/10.1023/A:1013222629919
  5. Wlaschek, M., Tantcheva-Poor, l., Naderi, L., Ma, w., Schneider, L. A., Razi-Wolf, Z., Schuller, J., and Scharffetter-Kochanek, K. (2001) Solar UV irradiation and dermal photoaging. J. Photochem Photobiol. B. 63(1): 41-51 https://doi.org/10.1016/S1011-1344(01)00201-9
  6. Bonte, F., Dumas, M., Chaudagne, C., and Meybeck, A. (1994) Influence of asiatic acid, madecassic acid, and asi-aticoside on human collagen l synthesis. Planta Med. 60(2): 133-5 https://doi.org/10.1055/s-2006-959434
  7. 중약대사전(中) (1977), 상해과학기술 출판사
  8. 장일무 (2003) 동양의약과학대전 l. 학술편수관
  9. Oikarinen, A, Autio, P., Kiistala, U., Risteli, L., and Risteli, J. (1992) A New method to measure Type I and III collagen synthesis in human skin In Vivo:Demonstration of decreased collagen synthesis after topical glucocorticoid treatment. J. Invest. Dermatol. 98(2): 220-225 https://doi.org/10.1111/1523-1747.ep12555884
  10. Jutley, J. K, Wood, E. J., and Cunliffe, W. J. (1993) Influence of retinoic acid and TGF-b on dermal fibroblast proliferation and collagen production in monolayer cultures and dermal equivalents. Matrix 13: 235-242 https://doi.org/10.1016/S0934-8832(11)80007-7
  11. Junichi M., Takeshi l., Nakahara M., and Hiroshi K. (1999) Cosmetics containing xanthoxol-skin lightening. JP99-316450
  12. Khadzhai Y l., Obolentseva G. V., and Prokopenko A. P.(l966) Relation between structure and spasmolytic activity in coumarin and furocoumarin derivatives. Sci.-Res. Chem. -Pharm. Inst. 29(2): 156-163