Korean Journal of Pharmacognosy (생약학회지)

The Korean Society of Pharmacognosy (한국생약학회)
권호 표지

Effects of Water and Methanol Extracts of Cricket (Gryllus bimaculatus) on Alcohol Metabolism

귀뚜라미의 물 및 메탄올 추출물이 알코올 대사에 미치는 효과

  • Lee, Yong-Woo (Department of Agricultural biology, National Institute of Agricultural Science & Technology, RDA) ;
  • Lim, Soon-Sung (Silver Biotechnology Research Center, Hallym University) ;
  • Ryu, Kang-Sun (Department of Agricultural biology, National Institute of Agricultural Science & Technology, RDA) ;
  • Lee, Heui-Sam (Department of Agricultural biology, National Institute of Agricultural Science & Technology, RDA) ;
  • Kim, Ik-Soo (Department of Agricultural biology, National Institute of Agricultural Science & Technology, RDA) ;
  • Kim, Jin-Won (Department of Agricultural biology, National Institute of Agricultural Science & Technology, RDA) ;
  • Ahn, Mi-Young (Department of Agricultural biology, National Institute of Agricultural Science & Technology)
  • 이용우 (농업과학기술원 농업생물부) ;
  • 임순성 (한림대학교 실버생물산업기술연구센터) ;
  • 류강선 (농업과학기술원 농업생물부) ;
  • 이희삼 (농업과학기술원 농업생물부) ;
  • 김익수 (농업과학기술원 농업생물부) ;
  • 김진원 (농업과학기술원 농업생물부) ;
  • 안미영 (농업과학기술원 농업생물부)
  • Published : 2004.06.30
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Abstract

The cricket has been used in East Asia as crude drugs for treating fever and hypertension, and is presently reared as a pharmaceutical insect in China and a food for animals. For the purpose of evaluating protective extracts against alcohol-induced toxicity, the extracts of the cricket (Gryllus bimaculatus) were examined in animal models acutely administered alcohol by the cricket in ICR-mice. Water and methanol extracts from the cricket, were found to cause a significant decrease (37%) in the blood ethanol concentration as well as enhancement of liver mitochondrial alcohol dehydogenase (ADH) and acetaldehyde dehydogenase (ALDH) activitieson on a single intraperitoneal administration in mice. Futhermore methanol extract was demonstrated to exhibit more potent enhancing activity on ethanol metabolism than water extract. These results suggest that water/alcohol extract of G. bimaculatus may be used as a food for reducing the toxicity of alcohol.

Keywords

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