A Monoacyldigalactosyl Glycerol from the Green Alga Enteromorpha prolifera

  • Kim, Ju-Sun (Natural Products Research Institute and College of Pharmacy, Seoul National University) ;
  • Shim, Sang-Hee (Natural Products Research Institute and College of Pharmacy, Seoul National University) ;
  • Lee, Sang-Hyun (Natural Products Research Institute and College of Pharmacy, Seoul National University) ;
  • Chae, Sung-Wook (Natural Products Research Institute and College of Pharmacy, Seoul National University) ;
  • Han, Sang-Jun (Natural Products Research Institute and College of Pharmacy, Seoul National University) ;
  • Kang, Sam-Sik (Natural Products Research Institute and College of Pharmacy, Seoul National University) ;
  • Lee, Yeon-Sil (Seokwon Life Science Research Institute, World Sea Green Co. Ltd.) ;
  • Jung, Sang-Hoon (Seokwon Life Science Research Institute, World Sa Green Co. Ltd.) ;
  • Shin, Kuk-Hyun (Seokwon Life Science Research Institute, Wold Sea Green.Co. Ltd.)
  • Published : 2004.12.30

Abstract

A monoacyldigalactosyl glycerol was isolated from the $CH_2Cl_2$ soluble fraction of the MeOH extract from the green alga Enteromorpha prolifera. The structure was established as $1-O-palmitoyl-3-O-[{\alpha}-D-galactopyranosyl(1{\rightarrow}6)-{\beta}-D-galactopyranosyl]-sn-glycerol$ (1) by chemical and spectroscopic methods.

Keywords

References

  1. Ambrosio, A.L., Sanz, L., Sanchez, E.I., Wolfenstein-Todel, C., and Calvete, J.J., Isolation of two mannan- and L-fucose-binding lectins from the green alga Enteromorpha prolifera: biochemical characterization of EPL-2. Arch. Biochem. Biophys. 415, 245-250 (2003) https://doi.org/10.1016/S0003-9861(03)00232-7
  2. Fusetani, N., and Hashimoto, Y, Structures of two water soluble hemolysins isolated from the green alga Vlva pertusa. Agric. BioI. Chem. 39,2021-2025 (1975) https://doi.org/10.1271/bbb1961.39.2021
  3. Higashi-Okai, K., Otani, S., and Okai, Y, Potent suppressive effect of Japanese edible seaweed, Enteromorpha prolifera (Sujiao-nori) on initiation and promotion phases of chemically induced mouse skin tumorigenesis. Cancer Lett. 140, 21-25 (1999) https://doi.org/10.1016/S0304-3835(99)00047-6
  4. Hiraga, Y, Kaku, K, Omoda, D., Sugihara, K, Hosoya, H., and Hino, M., A new digalactosyl diacylglycerol from a cultured marine dinot1agellate Heterocapsa circularisquama. J. Nat. Prod. 65, 1494-1496 (2002) https://doi.org/10.1021/np0201265
  5. Jung, J.H., Lee, H.K., and Kang, S.S., Diacylglycerylgalactosides from Arisaema amurense. Phytochemistry 42,447-452 (1996) https://doi.org/10.1016/0031-9422(95)00929-9
  6. Kang, S.S., Kim, J.S., Xu, Y.N., and Kim, Y.H., Isolation of a new cerebroside from the root bark of Aralia elata. J. Nat. Prod. 62, 1059-1060 (1999) https://doi.org/10.1021/np990018r
  7. Muse, J.O., Stripeikis, J.D., Fernandez, F.M., dHuicque, L. Tudino, M.B., Carducci, e.N., and Troccoli, O.E., Seaweeds in the assessment of heavy metal pollution in the Gulf San Jorge, Argentina. Environ. Pollut. 104,315-322 (1999) https://doi.org/10.1016/S0269-7491(98)00096-7
  8. Oh, Y.S., Lee, I.K and Boo, S.M., An annotated account of Korean economic seaweeds for food, medicinal and industrial uses. Kor. J. Phycol. 5,57-71 (1990)
  9. Rho, M.C., Matsunaga, K, Yasuda, K, and Ohizumi, Y, A novel monogalactosylacylglycerol with inhibitory effect on platelet aggregation from the Cyanophyceae Oscillatoria rosea. J. Nat. Prod. 59,308-309 (1996) https://doi.org/10.1021/np960088n
  10. Rowland, S.J., Yon, D.A, Lewis, C.A, and Maxwell, J.R, Occurrence of 2,6, I0-trimethyl-7-(3-methylbutyl)-dodecane and related hydrocarbons in the green alga Enteromorpha prolifera and sediments. Org. Geochem. 8,207-213 (1985) https://doi.org/10.1016/0146-6380(85)90028-2
  11. Shin, K.H., Development of health food for the treatment of diabetes and its complications from Korean seaweeds. The final report of the Korean Health 21 R&D Project (03-PJlPG11- YNOI-SY04-00 16), Seoul, 2004