Natural Product Sciences

The Korean Society of Pharmacognosy (한국생약학회)
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Helicobactericidal Activity of Cissus quadrangularis L. Variant I

  • Austin, Anoop (Research and Development, Herbal Cure Remedies) ;
  • M, Jegadeesan (Department of Siddha Medicine, Faculty of Sciences, Tamil University) ;
  • R., Gowrishankar (Department of Microbiology, SPK College)
  • Published : 2004.10.30
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Abstract

Cissus quadrangularis L. variant I (Family: Vitaceae), the common variant with square stem is widely used for peptic ulcer disorders (PUD) in traditional medicine. Aerial parts were collected during flowering and vegetative seasons and analysed. Aqueous (hot and cold) and solvent extracts (acetone, chloroform and ethanol) were screened for their anti-Helicobacter pylori (Hp) activities. Among them chloroform extract was observed to recover bioactive principles markedly with low minimal inhibitory concentration (MIC) and minimal lethal concentration (MLC). MIC was $30\;{\mu}g$ in both samples and MLC was $35\;{\mu}g$ for vegetative and $30\;{\mu}g$ for flowering seasons, respectively. Extracts from samples collected during flowering season were better than thse of vegetative season.

Keywords

References

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