대한한방소아과학회지 (The Journal of Pediatrics of Korean Medicine)
- 제18권2호
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- Pages.61-76
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- 2004
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- 1226-8038(pISSN)
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- 2287-9463(eISSN)
청상방풍탕(淸上防風湯)의 아토피성 알레르기 반응(反應) 조절(調節) 효과(效果)
Regulatory Effect of Atopic Allergic Reaction by Chungsangbangpoong-Tang
- 임태형 (원광대학교 한의과대학) ;
- 박은정 (원광대학교 전주한방병원 소아과) ;
- 이해자 (원광대학교 한의과대학 소아과학교실) ;
- 한경훈 (원광대학교 전주한방병원 소아과) ;
- 나원경 (원광대학교 전주한방병원 소아과) ;
- 진경선 (원광대학교 한의과대학 소아과학교실)
- Lim, Tae-Hyung (College of Oriental Medicine, Wonkwang University) ;
- Park, Eun-Jung (Department of Pediatrics, Jeonju Oriental Hospital, Wonkwang University) ;
- Lee, Hai-Ja (Department of Pediatrics, College of Oriental Medicine, Wonkwang University) ;
- Han, Kyeung-Hoon (Department of Pediatrics, Jeonju Oriental Hospital, Wonkwang University) ;
- Na, Won-Kyeung (Department of Pediatrics, Jeonju Oriental Hospital, Wonkwang University) ;
- Jin, Kyong-Son (Department of Pediatrics, College of Oriental Medicine, Wonkwang University)
- 발행 : 2004.12.31
초록
Objective : To demonstrate of regulatory effect of atopic allergic regulation by Chungsangbangpoong-Tang(CBT), This experiment was studied. Methods : The author investigated a possible effect of CBT on cytokines production using human T cell line (MOLT-4) or human mast cell line (HMC-1). In addition, the author investigated whether CBT has inhitory effects on compound 48/80- induced histamine release from rat peritoneal mast cells (RPMC) and compound 48/80-induced ear swelling in ICR mice. Results : CBT (0.01 mg/ml)-containing medium in stimulated culture supernatants significantly increased IL-2 secretion compared with untreated MOLT-4, whereas CBT (0.01-1.0 mg/ml)-containing medium in stimulated culture supernatants significantly decreased IL-4 secretion compared with untreated MOLT-4. Significant reduced levels of IL -6 and