The Journal of Pediatrics of Korean Medicine (대한한방소아과학회지)

The Association of Korean Oriental Pediatrics (대한한방소아과학회)
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An exprimental Study on the Effects of saruktanggamibangbangbang on Memory and Learning of Rats

사육탕가미방(四六湯加味方)이 흰쥐의 학습(學習) 및 기억(記憶)에 미치는 영향(影響)

  • Chang, Gyu-Tae (Department of pediatrics, College of Oriental Medicine, Dongguk University) ;
  • Kim, Jang-Hyun (Department of pediatrics, College of Oriental Medicine, Dongguk University) ;
  • Park, Bo-Kyoung (Department of pediatrics, College of Oriental Medicine, Dongguk University)
  • 장규태 (동국대학교 한의과대학 소아과학교실) ;
  • 김장현 (동국대학교 한의과대학 소아과학교실) ;
  • 박보경 (동국대학교 한의과대학 소아과학교실)
  • Published : 2004.08.31
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Abstract

Objective: This study was conducted to find out the effect of saruktanggamibang(SRT) on memory and learning of rats. Methods: The mon·is water maze was used. It was performed Acquisition test, Retention test of water maze. After Behavioral test, it was investigated AChE cell numbers of CAI and CA3 on hippocampus. Results: of water maze revealed that acqusitive abilities of SAP+SRT group significantly improved on 3, 4, 5th day compared with SAP+Saline group. Retention test of water maze didn't reveal that retentive abilities of SAP+SRT group significantly improved comparing with another group. ChAT cell numbers of medial septum of SAP+SRT group significantly increased compared with SAP+Saline group. AChE cell numbers of CAl and CA3 on hippocampus of Sham+SRT group significantly increased compared with Sham group. And AChE cell numbers of CAl and CA3 on hippocampus of SAP+SRT group significantly increased compared with SAP+Saline group. Conclusion: Saruktanggamibang(SRT) has an effect on memory and learning of rats.

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