The Journal of Pediatrics of Korean Medicine (대한한방소아과학회지)

The Association of Korean Oriental Pediatrics (대한한방소아과학회)
권호 표지

The Experimental study on the Anti-Stress effect of Yangsintang(YST)

양신탕(養神湯)의 항(抗)스트레스 효과(效果)에 대(對)한 실험적(實驗的) 연구(硏究)

  • Kim, Yun-Hee (Department of Pediatrics, College of Oriental Medicine, Daejon University) ;
  • Yoon, Ji-Yeon (Department of Pediatrics, College of Oriental Medicine, Daejon University)
  • 김윤희 (대전대학교 한의과대학 소아과학교실) ;
  • 윤지연 (대전대학교 한의과대학 소아과학교실)
  • Published : 2004.08.31
Download PDF
⟨ Previous Next ⟩

Abstract

Objective: The study aimed to evaluate the anti-stress effect of YST on the cold-stressed Mice. Method: The experimental animals were stressed in cold room ($4{\pm}0.5^{\circ}C$) for 1 hour in a day during 2weeks, and administerd 115mg/100g YST extract for 2weeks before stress. For 2weeks, we conducted a research about the change of weight and content of norepinephrine, epinephrine, dopamine, cortisol and GOT, GPT in the mice serum. Results: YST significantly inhibited the decrease of body weight induced by stress, compared with the control group. YST had no significant decreasing effect on the change of content of the serum GOT But decreased the content of the serum GPT. YST decreased the content of the serum cortisol. YST decreased the content of the serum dopamine a little and decreased the content of the serum epinephrine significantly. Conclusion: According to the above results, it is concluded that YST will be useful as a remedy against stress disease.

Keywords