Korean Journal of Acupuncture
- 제21권4호
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- Pages.101-115
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- 2004
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- 2287-3368(pISSN)
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- 2287-3376(eISSN)
고빈도 120 Hz 전침이 Cold-Restraint 스트레스 유발 흰쥐의 위점막에 미치는 영향(影響)
The Effects of 120 Hz High Frequency Electroacupuncture on the Gastric Mucosa in Cold-Restraint Stressed Rats
- 조미형 (동의대학교 한의과대학 침구경혈학교실) ;
- 안창범 (동의대학교 한의과대학 침구경혈학교실) ;
-
송춘호
(동의대학교 한의과대학 침구경혈학교실) ;
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윤현민
(동의대학교 한의과대학 침구경혈학교실) ;
-
김철홍
(동의대학교 한의과대학 침구경혈학교실) ;
- 장경전 (동의대학교 한의과대학 침구경혈학교실)
- Jo, Mee-Hyeong (Dept. of Acupuncture & Moxibustion, College of Oriental Medicine, Dong-Eui University) ;
- Ahn, Chang-Beohm (Dept. of Acupuncture & Moxibustion, College of Oriental Medicine, Dong-Eui University) ;
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Song, Choon-Ho
(Dept. of Acupuncture & Moxibustion, College of Oriental Medicine, Dong-Eui University) ;
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Yoon, Hyoun-Min
(Dept. of Acupuncture & Moxibustion, College of Oriental Medicine, Dong-Eui University) ;
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Kim, Cheol-Hong
(Dept. of Acupuncture & Moxibustion, College of Oriental Medicine, Dong-Eui University) ;
- Jang, Kyung-Jeon (Dept. of Acupuncture & Moxibustion, College of Oriental Medicine, Dong-Eui University)
- 발행 : 2004.12.27
초록
Objective : The present studies investigated the effects of 120 Hz high frequency electroacupuncture (EA) on the stress-induced stomach dysfunction in relation to its effect on the level of stress hormones and gastric mucosal damages. The gastric mucosal injury was induced by cold-restraint stress and two acupoints corresponding to Zusanli and Sanyinjiao in man were used. Methods : Cold-restraint stress produced typical gastric lesions in all rats of the stressed groups, but the number of ulcers as well as the mean ulcer diameter were reduced by 120 Hz EA pre-treatment. Results : The degranulation value of gastric mast cell was significantly higher in cold-restrained rats than in control ones. However, with the significant reduction of degranulation values of gastric mast cells in EA pre-treated rats compared with cold-restrained rats. Cold-restarint stress induced an elevated mRNA expression of pro-inflammatory gene such as cyclooxygenases-2 and tumor necrosis factor