Korean Journal of Acupuncture
- Volume 21 Issue 2
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- Pages.111-123
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- 2004
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- 2287-3368(pISSN)
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- 2287-3376(eISSN)
Effects of Cordyceps militaris Mycelia(CMM) herbal acupuncture at BL13, LU4 on airway smooth muscle, airway inflammation, IgE and Interleukin-4 in mouse model of allergic bronchial asthma
동충하초(冬蟲夏草) 약침(藥鍼)이 백서(白鼠)의 기관지평활근(氣管支平滑筋) 장력(張力)과 염증(炎症) 및 면역(免疫) 반응(反應)에 미치는 영향(影響)
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Youn, Dae-Hwan
(Dept. of Meridian & Acupoint, College of Oriental Medicine, Dongshin University) ;
- Choi, Gwan-Jun (Dept. of Acupuncture & Moxibustion, College of Oriental Medicine, Dongshin University) ;
- Chae, Woo-Seok (Dept. of Acupuncture & Moxibustion, College of Oriental Medicine, Dongshin University) ;
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Na, Chang-Su
(Dept. of Meridian & Acupoint, College of Oriental Medicine, Dongshin University)
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윤대환
(동신대학교 한의과대학 경혈학교실) ;
- 최관준 (동신대학교 한의과대학 침구학교실) ;
- 채우석 (동신대학교 한의과대학 침구학교실) ;
-
나창수
(동신대학교 한의과대학 경혈학교실)
- Published : 2004.06.27
Abstract
Objectives : It has been reported that Cordyceps militaris Mycelia(CMM) has an effect on deficiency allergic asthma(虛喘) clinically. The aim of this study was to determine an appropriate oriental treatment and the doses of CMM to treat asthma. Methods : In order to study the effect of herbal acupuncture solution of the CMM on allergic asthma, the mouse were pretreated by CMM herbal acupuncture at BL13, LU4 before antigen sensitization. 2 days later Mice were actively sensitized with a subcutaneous injection of ovalbumin(OA) and 13 days later they were provoked with OA aerosols. IL-4, lymphocyte, macrophage in bronchoalveolar lavage fluid(BALF), IgE in serum, WBC, RBC, HGB in blood, and in vitro isometric contractile responses of the isolated tracheal smooth muscle(TSM) to acetylcholine
Keywords
- allergic bronchial asthma;
- ordyceps militaris Mycelia(CMM);
- herbal acupuncture;
- airway inflammation;
- IgE;
- Interleukin-4