Bulletin of the Korean Chemical Society

Korean Chemical Society (대한화학회)
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Synthesis of Oxazolidinone Phosphonate Derivatives, Part I

  • Hwang, Jae-Min (Department of Environmental & Applied Chemistry, College of Engineering, Kangnung National University) ;
  • Shin, Woon-Seob (Department of Microbiology, Kwandong University College of Medicine) ;
  • Jung, Kang-Yeoun (Department of Environmental & Applied Chemistry, College of Engineering, Kangnung National University)
  • Published : 2004.09.20
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Abstract

Several new derivatives of oxazolidinone phosphonate, that are expected to show biological activity, were prepared efficiently by previously published methods. ${\gamma}$-Ketophosphonate 1 was synthesized using pentacovalent oxaphosphorane chemistry followed by reductive amination with aromatic amine of oxazolidinone 4. Biological activity of the synthetic compounds has been studied. One of the synthetic compounds showed promising result for us to pursue further studies.

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References

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