한방안이비인후피부과학회지 (The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology)
- 제16권3호
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- Pages.96-115
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- 2003
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- 1738-6640(pISSN)
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- 2234-4020(eISSN)
아토피 피부염을 유발한 동물모델에서 消風淸營湯加味方이 각질층 기능회복에 미치는 영향
The Effect of Sopungchengyoungtanggami-bang Extract to Recover Function of Stratum Corneum on Mice Model after Atopic Dermatitis Elicitation.
- 발행 : 20031200
초록
Introduction and Objectives : Administrating the Sopungchengyoungtanggami-bang (SCG) extract on to the atopic dermatitis(AD) is to study change of external dermal formation, change of leukocytes in vasculature, change of lipid formation in stratum corneum and distribution of ceramide and this study is done through forcing injury to rat's back skin which are lipid protect formation in stratum corneum. Materials and Methods : The AD which caused intentionally using the external application on the rat's back skin was used the SCG. The change of leukocytes in vasculature has been identified through optima 5.2 and student t-test and the results were made into dermal formation graph. Results : After dispensing SCG extract into the AD, the dermal injury was decreased. Especially, recover of lipid protection formation which include lipid and ceramide in stratum corneum is suppressing acute inflammation that some factors are PKC, TNF-