A Case of Primary Extranodal NK/T Cell Lung Lymphoma Presenting as Multiple Patchy Pulmonary Infiltrations

다발성 반점형 폐침윤으로 발현한 원발성 NK/T 세포 폐림프종

  • Jung, Gum Mo (Department of Internal Medicine, Presbyterian Medical Center) ;
  • Kwak, Jin Young (Department of Internal Medicine, Presbyterian Medical Center) ;
  • Choi, Hyun Jong (Department of Internal Medicine, Presbyterian Medical Center) ;
  • Park, Hyo Suk (Department of Internal Medicine, Presbyterian Medical Center) ;
  • Chang, Myoung (Department of Thoracic Surgery, Presbyterian Medical Center) ;
  • Lee, Kwang Min (Department of Pathology, Presbyterian Medical Center) ;
  • Kim, Nam Don (Department of Internal Medicine, Korea Cancer Center Hospital) ;
  • Park, Yong Jin (Department of Internal Medicine, Korea Cancer Center Hospital) ;
  • Kim, Kwi Wan (Department of Internal Medicine, Presbyterian Medical Center)
  • Published : 2003.12.30

Abstract

Primary lung lymphoma is an uncommon tumor, which constitutes 0.5% of primary lung cancer, and 3% of extranodal lymphoma. The most frequent radiologic presentation of pulmonary parenchymal lymphoma is single mass or nodule. But we have experienced a case which was radiologically presented as patchy lung infiltration at first, and then progressive multiple reticulonodular infiltrations in lung. A 48-year-old woman was admitted to the hospital because of fever and cough. Chest PA obtained on admission revealed multiple patchy infiltration. Eventually, open lung biopsy was performed and the specimen disclosed extranodal NK/T cell lymphoma, and in bone marrow aspiration, hemophagocytosis was present. We report a case of primary extranodal NK/T cell lung lymphoma presented as patchy lung infiltrations, which was treated with chemotherapy.

저자들은 기침, 호흡곤란 등의 호흡기 증세와 발열, 체중감소 등의 전신증상이 있으면서 흉부 방사선 소견상 폐렴이 의심되었으나 광범위 항생제에 반응이 없이 빠르게 진행하는 환자에서 개흉 폐생검을 통해 NK/T 세포 림프종을 경험하였기에 문헌고찰과 함께 보고하는 바이다.

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